ID S9VUS6_SCHCR Unreviewed; 514 AA.
AC S9VUS6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Triglyceride lipase-cholesterol esterase {ECO:0000313|EMBL:EPY49914.1};
GN ORFNames=SPOG_03383 {ECO:0000313|EMBL:EPY49914.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY49914.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY49914.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE546994; EPY49914.1; -; Genomic_DNA.
DR RefSeq; XP_013025252.1; XM_013169798.1.
DR AlphaFoldDB; S9VUS6; -.
DR STRING; 653667.S9VUS6; -.
DR EnsemblFungi; EPY49914; EPY49914; SPOG_03383.
DR GeneID; 25037700; -.
DR eggNOG; KOG2624; Eukaryota.
DR HOGENOM; CLU_010974_5_0_1; -.
DR OMA; DGEHVDC; -.
DR OrthoDB; 5474043at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR11005:SF158; LIPASE C1672.09-RELATED; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 124..418
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 446..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 514 AA; 60135 MW; EDAFBEC8DF590C40 CRC64;
MLRLPFIRRL KWNEYVSLFL GILFVTFEKL LSGVVFAIHI ILRPIWTNYI KRMTKRYPEK
HQSPFVERAR AIHDADDIRQ MCNISGYNVE EHLVRTQDDY ILCIHRISKD KPGKIGMPIP
KKLPVVYCHH GLLMNSEVWV CNIDQRNCLV YQLVDQGYDV WLGNNRGNKY SRQHLRFDST
DVDFWNFSID DFAHYDIPDT IDYILKTSEQ KQLTYIGFSQ GTAQAFAALS VQPLLNEKVN
SFIALAPAMS PKGLHNRIVD AFVKARPSIL FFLFGRKSIL PSAGFWQSIL PNVLFNRILS
FCLAQLFNWS CESMSPLQRH ASFAHLYSYT SVKCLVHWFQ IMRSAEFRMY DNDQIVHDYF
SKHYRAARFP TKNIRTPILL FWGDSDSLVD IQPMLNSLPP MAEQIRIPGY EHLDMIWADT
THKYVIPSVL ERLSIIYAGT QSKENADEKA VNLHKPRKQK AHEEDLDFQE EEAEEERKVE
RLSIRNKKSK RKWGSNLDDE DTKKLYQSNV NSNI
//
