ID S9W2R5_SCHCR Unreviewed; 1338 AA.
AC S9W2R5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN ORFNames=SPOG_04214 {ECO:0000313|EMBL:EPY54323.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY54323.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY54323.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC4 subfamily.
CC {ECO:0000256|ARBA:ARBA00006005}.
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DR EMBL; KE546988; EPY54323.1; -; Genomic_DNA.
DR RefSeq; XP_013021929.1; XM_013166475.1.
DR STRING; 653667.S9W2R5; -.
DR EnsemblFungi; EPY54323; EPY54323; SPOG_04214.
DR GeneID; 25038527; -.
DR eggNOG; KOG0996; Eukaryota.
DR HOGENOM; CLU_001042_4_1_1; -.
DR OMA; CPALDNM; -.
DR OrthoDB; 231904at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR GO; GO:0000796; C:condensin complex; IEA:EnsemblFungi.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:EnsemblFungi.
DR GO; GO:1990814; F:DNA/DNA annealing activity; IEA:EnsemblFungi.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:EnsemblFungi.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:EnsemblFungi.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF172; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 2.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 652..765
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 380..505
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 549..614
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 812..912
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1012..1060
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1338 AA; 151848 MW; BB0C5C4C2E2E4554 CRC64;
MSDKRPARTS SVPSIVDATP DRAERPRKQV RQVVTTPSRS EDPSRIVKLE QTPSQGFHSE
FLKKRITDSL RERPNLLNKF ISANQETPSK ASVPNPFNSS NAEDSSLIED AITGQDNLDV
LAPRLIVYQL TLKNFKSYAG TQIIGPFHPS FSSIVGPNGS GKSNVIDALL FVFGFRASKL
RQTKASALIH KSAAHPSLDS CDVEIVFKEV DPDSNYIDGS ELSIRRSAYK NNVSKYFLNN
VESSFSTVSN VLKERGIDLN HKRFLILQGE VESIAQMKPK AMTENDDGLL EYLEDIIGTS
KYKPIIEEKI NELSTLNDVC NEKENRFNLV VAERNKLESS KNEVLDILRD ENNLYRKLHT
LYQLNLFELN SKKVLITNML QKLEDSYKSK NANFEENEKV VFEMTEELTQ LKSKVQDLKN
SNRAEKRERQ RYEQQAVKIE EKLKHLSSKQ KKTQKQLETL SANKSELQYS LDTHDDVHQR
LTQEIEEISS KLSSEEDQLN KIRESLRGKT EGISNAIEEK QKLMAPSEKK VNELNSVKQV
TKAELDMLFE QEKSLNEEQQ NAKSSLENLI AEQKEKTLLL NSKKNHHNTI KKDSQSLERN
ISDLRRKKSE LHRVIAQSRV KLEEMKATLS SSRSRGNVLG GLQTLHDSGQ LEGFHGRLGD
LGTIDSKYDV AISTACPALN HIVVDSLEVG QKCIAFLRSN NLGRSSFIVL RALQERNLKP
IQTPENVPRL FDLLHFKNEI FAPAFFSVLQ NTLVADNLEQ ANRIAFGKTR WRVVTLSGQL
IDKSGTMTGG GTRVKQGGMA SQLPSDISPV SLSNAEDQTT DAENRHRQVS EELVALLEKS
DELKNEAPCL ELEISKLHLD LSAFNNLVEG AKNQVSNSRK ALKEERSLQE RKQKLTGDLT
KLDQQIDNIK ASNGGLVAEV RELQDKIMQI GGIKYRIQKS KVDDLHEQHK YIKEKLTNVS
FEKRKNEQRV HSIIGELESL QSDFSTTQKE LETNETDFNL LRGKIKDYTT KIDELSNSIH
DINDSINELN NRIDFESKEI NSMKAERLDL ENKLTEQKTA HSDVLHNEKK LQKLLSELIL
HDLREYDQSE ARAPEFQEFS EDELASMNKQ SLYEGISEFK KKTEEKEVDV GVLQSYLRCT
KEVEKRASDF EADTRKRNNV KQTVTDLQTQ RLDEFMEGFG NISQKLKAMY QIITMGGNAE
LELVDSLDPF SEGVLFSIMP PKKSWKNISN LSGGEKTLSS LALVFALHSY KPTPLYVMDE
IDAALDFKNV SIVANYIKER TKNAQFIVIS LRSNMFELSS RLVGIYKTAN MTKSVTINNR
DLQVNAEKDS DHSPSQVN
//
