ID S9W8M0_CAMFR Unreviewed; 1492 AA.
AC S9W8M0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
GN ORFNames=CB1_081801001 {ECO:0000313|EMBL:EPY72818.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY72818.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY72818.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family.
CC Adhesion G-protein coupled receptor (ADGR) subfamily.
CC {ECO:0000256|ARBA:ARBA00007343}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
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DR EMBL; KB019685; EPY72818.1; -; Genomic_DNA.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR001759; Pentraxin-related.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF277; ADHESION G-PROTEIN COUPLED RECEPTOR G4; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS51828; PTX_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1337..1354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1366..1387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1407..1427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1328..1418
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 314..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1492 AA; 162045 MW; 74CCF4C97BDE5321 CRC64;
MKEHITYQRL FGLILMSSLI FLSDALSLKG KRLDFYRGAD TYVSLATTIP ELSRFTVCID
LVFVGGKSSG WMAFSYITNN TFLGREDIDL GLAGDHQQLI VYNLGKTFYI RYQLTPFQWH
TICLIWDGVK GRLELFLNKE RILVMMDQPQ HLTPNGTLVL GHFLKKGDNQ VKSMVPRFTN
SLYYFQLWDH ILENEEFMKC LSGNVVSWEE DVWLVNKIIP TFDVRLRCSA IALSTKSTSI
GPTTNSAKIT KSTSSESTRT ARMAESVATE TFHPTVATNF LYTSEFTKNS TVSKTSVTGS
QSAVMRTTSL FSSIESTSMP TTSRPKHKST GIGASTASGS VPWSTVEQTS ATTTHIGTAS
TLPPESVLIS TATPVDSVFP GNQTASMLAT TDMEIPFTVF PTESIEMTPA LRTAEIKSTS
INFRDVSSPR MEDTVSTSAP KEASSMALSF RTSSPFTGAQ SVQTVIDAET THTAGTPGVT
LAPTVAQTML SPTITGPEYT QNTPTGGENM LPLISTESAS TSKAFQSGPT SITDEDDHLP
STNEITWTSR PDQTLLTSAF HGSTSNTEHA STNTNTIIPP ETSTENEATT TADATTDRYT
TVLSNLTSPR FANFSTVTGT TSVTKLPECK LTTLLLKTTP TSTVAENELL STPRETVVLP
VDIVSTLADV EPNFSTEESA SENTQTETNG IIAFGETTDP VPESATTERF KTPVTREETT
SHYLKGKLTL AATTEVFPFA TMLEATDESV SPFLDLEKLT ARLDNKTATT EVRGSWFSTK
LVKTTPKSSY NGTTEIFNST HIYTANWTSE TLPEGNPTPS PTSGNTQSLP KSLDASTTLG
TSYVTIPKDR TAVSLSAGTF PPQPAASHSS APLVPSTHMF SLPVHVSAVA SMVVSEETKA
ITPEPSTLAR ASSTSMPSDV STLSSAMVTT ASVPPLDQTA STTSDTVPTH RDSLHTASEA
TVISVRMTPT PVPSLTETLI PSLRPPTPVA TKAETTLLST SADAVTPSRP ILACSKSPPD
NTPVVSSTHV TSSLSTPLAT QPISQAEETS THALSFPYTF SGSGDAGLAT GTTETSAVDE
TVPSHISANK LITSGDGNFD FTYCRYGQSS ISINTGKSHW EKPKFKQCKL LQELPNKIVD
LANITISDEN ANDVAEHIFN LINESPLLDE EETKTIVSKV SDISQCDEIS MNLTQTILQI
IDAALGKQNN SLSDLHEVSN EILRIIERAG HKMEFSGRTA NLTVARLALA VLRVDHTFEG
MAFSIRSFEE GTDPETKNVA KALTTYVVSA SISDTSIQNL ADPVVITLQH IEGKRMGKVD
GIRQAVNKLR KDHPSKILIN LCTALLMLNL VFLLNSWSSS FPQAGLCITA AVALHYFLLV
SLTWMGLEAV HMYLALVKVF NIYFPNYILK LCLAGWGFLI FVFHCVMKER VREQWQLHFC
CGWLRLDNSS DNFDEDPNCF SPVSCEAVPN CVRRLLPVEI KMNSIDKQRF LH
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