ID S9X2F9_CAMFR Unreviewed; 315 AA.
AC S9X2F9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Metal transporter {ECO:0000256|RuleBase:RU369091};
GN ORFNames=CB1_000642055 {ECO:0000313|EMBL:EPY82598.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY82598.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY82598.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- FUNCTION: Metal transporter. {ECO:0000256|RuleBase:RU369091}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU369091};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU369091}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ACDP family. {ECO:0000256|ARBA:ARBA00010484,
CC ECO:0000256|RuleBase:RU369091}.
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DR EMBL; KB016912; EPY82598.1; -; Genomic_DNA.
DR AlphaFoldDB; S9X2F9; -.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF22; METAL TRANSPORTER CNNM2; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 13..37
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369091"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369091"
FT TRANSMEM 98..117
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369091"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369091"
FT DOMAIN 9..189
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
SQ SEQUENCE 315 AA; 35554 MW; E7CF0F4D6158C47C CRC64;
MIVGEEKKFL LPFWLQVIFI SLLLCLSGMF SGLNLGLMAL DPMELRIVQN CGTEKEKNYA
KRIEPVRRQG NYLLCSLLLG NVLVNTTLTI LLDDIAGSGL VAVVVSTIGI VIFGEIVPQA
ICSRHGLAVG ANTIFLTKFF MMMTFPASYP VSKLLDCVLG QEIGTVYNRE KLLEMLRVTD
PYNDLVKEEL NIIQGALELR TKTVEDVMTP LRDCFMITGE AILDFNTMSE IMESGYTRIP
VFEGERSNIV DLLFVKDLAF VDPDDCTPLK TITKFYNHPL HFVFNDTKLD AMLEEFKKEL
KQETTNPTNT EKERQ
//
