ID S9XG41_CAMFR Unreviewed; 907 AA.
AC S9XG41;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CB1_000106009 {ECO:0000313|EMBL:EPY89482.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY89482.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY89482.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
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DR EMBL; KB016405; EPY89482.1; -; Genomic_DNA.
DR AlphaFoldDB; S9XG41; -.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd18523; BACK_BTBD2; 1.
DR CDD; cd14173; STKc_Mnk2; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.60.120.820; PHR domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR012983; PHR.
DR InterPro; IPR038648; PHR_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45774; BTB/POZ DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR45774:SF6; BTB_POZ DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF08005; PHR; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000030684}.
FT DOMAIN 174..458
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 479..545
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 128..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..901
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 203
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 907 AA; 100640 MW; 2FF1F9595E6DE8B6 CRC64;
MPHLGDTPTL ELYLRNRDPC VLIQRALPLG LCPCFSSKVA AAVEPHAMAP GLPEPVSAVS
GEAELELCDS NRPLHMPTNF TLKPSGVRHP CGYRTKTPHH LPAEPREGQN PFELAFSLDQ
AHHGETDFSL ECPTRPDMPA SQPIDIPDAK KRGKKKKRCR ATDSFSGRFE DVYQLQEDVL
GEGAHARVQT CVNLITNQEY AVKIIEKQPG HIRSRVFREV EMLYQCQGHR NVLELIEFFE
EEDRFYLVFE KMRGGSILSH IHKRRHFNEL EASVVVQDVA SALDFLHNKG IAHRDLKPEN
ILCEHPNQVS PVKICDFDLG SGIKLNGDCS PISTPELLTP CGSAEYMAPE VVEAFSEEAS
IYDKRCDLWS LGVILYILLS GYPPFVGHCG SDCGWDRGEA CPACQNMLFE SIQEGKYEFP
EKDWAHISFA AKDLISKLLV RDAKQRLSAA QVLQHPWVQG CAPENTLPTP MVLQRVNCLE
VTLLTFQSLN AIIKFVLAVG SAVFDAMFNG GMATTSTEIE LPDVEPAAFL ALLKFLYSDE
VQIGPETVMT TLYTAKKYAV PALEAHCVEF LKKNLRADNA FMLLTQARLF DEPQLASLCL
ENIDKNTADA ISAEGFTDID LDTLVAVLER DTLGIREVRL FNAVVRWSEA ECQRQQLQVT
PENKRKVLGK ALALIRFPLM TIEEFAAGPA QSGILVDREV VSLFLHFTVN PKPRVDFIDR
PRCCLRGKEC SINRFQQVES RWGYSGTSDR IRFSVNKRIF VVGFGLYGSI HGPTDYQVNI
QIIHTDSNTV LGQNDTGFSC DGSASTFRVM FKEPVEVLPN VNYTACATLK GPDSHYGTKG
LRKVTHESPT TGAKTCFTFC YAAGNNICPG SCNSVQLGTA SCNRKTSPTP IAVQQGPDQE
TPPTPAL
//
