ID SRR1_CANTT Reviewed; 264 AA.
AC C5M3F1;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Stress response regulator protein 1;
GN Name=SRR1; ORFNames=CTRG_00590;
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Required for stress adaptation, morphogenesis and virulence.
CC {ECO:0000250}.
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DR EMBL; GG692395; EER35851.1; -; Genomic_DNA.
DR RefSeq; XP_002545809.1; XM_002545763.1.
DR AlphaFoldDB; C5M3F1; -.
DR SMR; C5M3F1; -.
DR STRING; 294747.C5M3F1; -.
DR EnsemblFungi; CTRG_00590-t43_1; CTRG_00590-t43_1-p1; CTRG_00590.
DR GeneID; 8296882; -.
DR KEGG; ctp:CTRG_00590; -.
DR VEuPathDB; FungiDB:CTRG_00590; -.
DR eggNOG; ENOG502SFN6; Eukaryota.
DR HOGENOM; CLU_065405_0_0_1; -.
DR OrthoDB; 12386at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0036180; P:filamentous growth of a population of unicellular organisms in response to biotic stimulus; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:1900445; P:positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus; IEA:UniProt.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR44591:SF3; RESPONSE REGULATORY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44591; STRESS RESPONSE REGULATOR PROTEIN 1; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..264
FT /note="Stress response regulator protein 1"
FT /id="PRO_0000413388"
FT DOMAIN 138..256
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT REGION 50..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..74
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 189
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 264 AA; 30190 MW; 14C07C98141FE869 CRC64;
MNYIMCRNNL SQSSLPQLSS SAVNDANIDY FSLKPKLSLD TNSSGNSEII YSDCDNNKNN
NDDDDDDDDY NKDTYDELLD PFDTIAVNQH DLEYYSPLTP FEIQNTSPQD SIISSKSSNK
SNSLQPFPLT LPNLTNYRFL IVDDNIINLK ILNRVLLKLY PRSNIVQVQD SKLVNEILQR
QHFDSVFLDI EMPDITGIDI AKFIRSDERF NQMAVIAVTT RNSAKDLQQY KECGIDHTFH
KPLNYSLDLI GGSIDDIIER RKSL
//
