ID T0BRT7_ALIAG Unreviewed; 688 AA.
AC T0BRT7; A0A9E6ZQC7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:UNO48530.1};
GN ORFNames=K1I37_17995 {ECO:0000313|EMBL:UNO48530.1};
OS Alicyclobacillus acidoterrestris (strain ATCC 49025 / DSM 3922 / CIP 106132
OS / NCIMB 13137 / GD3B).
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Alicyclobacillus.
OX NCBI_TaxID=1356854 {ECO:0000313|EMBL:UNO48530.1, ECO:0000313|Proteomes:UP000829401};
RN [1] {ECO:0000313|Proteomes:UP000829401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3922 {ECO:0000313|Proteomes:UP000829401};
RX PubMed=36240455; DOI=10.1093/g3journal/jkac225;
RA Leonardo I.C., Barreto Crespo M.T., Gaspar F.B.;
RT "Unveiling the complete genome sequence of Alicyclobacillus acidoterrestris
RT DSM 3922T, a taint-producing strain.";
RL G3 (Bethesda) 12:0-0(2022).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP080467; UNO48530.1; -; Genomic_DNA.
DR RefSeq; WP_021297793.1; NZ_AURB01000162.1.
DR STRING; 1356854.N007_13705; -.
DR KEGG; aaco:K1I37_17995; -.
DR Proteomes; UP000829401; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000829401}.
FT DOMAIN 59..222
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 274..653
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 688 AA; 75003 MW; C7AFC0F8F5B71EED CRC64;
MNQDKPKKMK KMLRINTVYF IIFLSFTGLI LRGAYVQIVK GPTFRNAEVN TQFVRVAETP
QRGWIYDANG QVLAWDTPSD TIVLDNFTSI PKTTLHNIAN ELAPVLNKTP QALYHTMTTD
KTDLQIPLET NATKSQIAYV VEHKSDLPNV EITQTYQRQY PEGDLAGQVL GYVSSITAEN
KNQYLNKGYI VSQKVGTTGI EQEYESKLQG KPGEELLTVD PSTGTVQTVG SAPAATPGDN
LQLTLDGHMQ AEAQNIIMND INSSDNKSLI TNAAAVMLNV KTGGVISMVS YPYLNPNWFT
SGKPMTSAQV NYLENSGAQL NNAIQDIQNP GSTVKPANLL TALKQGAVTP DYSLDDEGGL
YIGKTWLNED EGMRFGWLDP IRAIAVSSDV FFYQVGLRLG KWFGSSSVSG GSYPPSDGSY
QHYLNTDFAK GINALFQGEW DFGLGPKTGI DLPGEESGKF YIYDTSKEEE VPYDLQASEE
SIKKTGEYAN NGTPASLAEA GIGQSQSFTT MQLAEYAMTL ANNGKKLQPH LLDKVYSPTD
TPTNGAKPLS TVKTKVTGQV GGSQTYYDLI KQAMYEVTTG GQDATANGLF TDAPYKVAAK
TGTAQITIHN QKTDNSVFIC YAPLDHPQVA MAIMIPGGGY GASLAGRIAR QMLDAYFDEH
HASFMPKQDW TNTKIPSNWL SSPANQLP
//
