ID T0CKH8_ALIAG Unreviewed; 343 AA.
AC T0CKH8; A0A9E6ZF02;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase PdxA {ECO:0000313|EMBL:UNO48510.1};
DE EC=1.1.1.262 {ECO:0000313|EMBL:UNO48510.1};
GN Name=pdxA {ECO:0000313|EMBL:UNO48510.1};
GN ORFNames=K1I37_17895 {ECO:0000313|EMBL:UNO48510.1};
OS Alicyclobacillus acidoterrestris (strain ATCC 49025 / DSM 3922 / CIP 106132
OS / NCIMB 13137 / GD3B).
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Alicyclobacillus.
OX NCBI_TaxID=1356854 {ECO:0000313|EMBL:UNO48510.1, ECO:0000313|Proteomes:UP000829401};
RN [1] {ECO:0000313|Proteomes:UP000829401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3922 {ECO:0000313|Proteomes:UP000829401};
RX PubMed=36240455; DOI=10.1093/g3journal/jkac225;
RA Leonardo I.C., Barreto Crespo M.T., Gaspar F.B.;
RT "Unveiling the complete genome sequence of Alicyclobacillus acidoterrestris
RT DSM 3922T, a taint-producing strain.";
RL G3 (Bethesda) 12:0-0(2022).
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|ARBA:ARBA00001968};
CC -!- SIMILARITY: Belongs to the PdxA family. PdxA2 subfamily.
CC {ECO:0000256|ARBA:ARBA00009464}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP080467; UNO48510.1; -; Genomic_DNA.
DR STRING; 1356854.N007_18740; -.
DR KEGG; aaco:K1I37_17895; -.
DR Proteomes; UP000829401; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR005255; PdxA_fam.
DR NCBIfam; TIGR00557; pdxA; 1.
DR PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR Pfam; PF04166; PdxA; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:UNO48510.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000829401}.
SQ SEQUENCE 343 AA; 36226 MW; 2871C7A22A68F54E CRC64;
MTKKTRIAVT MGDPAGIGPE ITLMGLQDKA IAEQVEAVVV GDVNRLEVAK AALVKTGRLS
ANQVTLRPIG DVSEAAYQPG VMDVLDQNNV PSDLPWGKVS AEAGAAAFDY VKKSVELAVA
KQVDAICTAP INKEAWKLAH VPYPGHTEAL AALSGSDKSA MMLVNHGLRV VHVTTHVSLK
DAIAMATTNR VFERIQLTVR SLEQFGMKRP RIAVAGINPH AGEGGLFGRE DIEQIAPAIE
QAKQAGMDVS GPWPPDSIYA RAAGGEFDAV IAMYHDQGHI AIKMLGFDTG INVTLGLPIL
RTSVDHGTAF DIAGKGIARE QSMVQSLQVA IDFLQGKAAG AAQ
//
