ID T0DXL0_HELPX Unreviewed; 567 AA.
AC T0DXL0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Flagellar M-ring protein {ECO:0000256|PIRNR:PIRNR004862};
GN ORFNames=N206_04615 {ECO:0000313|EMBL:EPZ74730.1};
OS Helicobacter pylori UM111.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1352345 {ECO:0000313|EMBL:EPZ74730.1, ECO:0000313|Proteomes:UP000015461};
RN [1] {ECO:0000313|EMBL:EPZ74730.1, ECO:0000313|Proteomes:UP000015461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UM111 {ECO:0000313|EMBL:EPZ74730.1,
RC ECO:0000313|Proteomes:UP000015461};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- FUNCTION: The M ring may be actively involved in energy transduction.
CC {ECO:0000256|PIRNR:PIRNR004862}.
CC -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body
CC {ECO:0000256|ARBA:ARBA00004117, ECO:0000256|PIRNR:PIRNR004862}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FliF family. {ECO:0000256|ARBA:ARBA00007971,
CC ECO:0000256|PIRNR:PIRNR004862}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPZ74730.1}.
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DR EMBL; AUSR01000002; EPZ74730.1; -; Genomic_DNA.
DR RefSeq; WP_021308505.1; NZ_AUSR01000002.1.
DR AlphaFoldDB; T0DXL0; -.
DR PATRIC; fig|1352345.3.peg.331; -.
DR Proteomes; UP000015461; Unassembled WGS sequence.
DR GO; GO:0009431; C:bacterial-type flagellum basal body, MS ring; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR013556; Flag_M-ring_C.
DR InterPro; IPR000067; FlgMring_FliF.
DR InterPro; IPR006182; FliF_N_dom.
DR InterPro; IPR043427; YscJ/FliF.
DR NCBIfam; TIGR00206; fliF; 1.
DR PANTHER; PTHR30046; FLAGELLAR M-RING PROTEIN; 1.
DR PANTHER; PTHR30046:SF0; FLAGELLAR M-RING PROTEIN; 1.
DR Pfam; PF01514; YscJ_FliF; 1.
DR Pfam; PF08345; YscJ_FliF_C; 1.
DR PIRSF; PIRSF004862; FliF; 1.
DR PRINTS; PR01009; FLGMRINGFLIF.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|PIRNR:PIRNR004862};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000313|EMBL:EPZ74730.1};
KW Cilium {ECO:0000313|EMBL:EPZ74730.1}; Coiled coil {ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000313|EMBL:EPZ74730.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..221
FT /note="Flagellar M-ring N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01514"
FT DOMAIN 257..423
FT /note="Flagellar M-ring C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08345"
FT REGION 322..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 489..516
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 567 AA; 63595 MW; FC0D1C88FE6007B2 CRC64;
MDLKVLLQRI VDFFIKLNKK QKIALIAAGV LITALLVFLL LYPFKEKDYA QGGYGVLFER
LDSSDNALIL QHLQQNQIPY KILKDDTILI PKDKVYEERI TLASQGIPKT SKVGFEIFDT
KDFGATDFDQ NIKLIRAIEG ELSRTIESLN PILKANVHIA IPKDSVFVAK EVPPSASVML
KLKPDMKLSP TQILGIKNLI AAAVPKLTTE NVKIVNENGE SIGEGDILEN SKELALEQLR
YKQNFENILE NKIVNILAPI VGGKNKVVAR VNAEFDFSQK KSTKETFDPN NVVRSEQNLE
EKKEGAPKKQ VGGVPGVVSN IGPVQGLKDN KEPEKYEKSQ NTTNYEVGKT ISEIKGEFGT
LVRLNAAVVV DGKYKIALKD GANTLEYEPL SDESLKKINA LVKQAIGYNQ NRGDDVAVSN
FEFNPTAPML DNATLSEKIM HKTQKVLGSF TPLIKYILVF IVLFIFYKKV IVPFSERMLE
VVPDEDKEVK SMFEEMDEEE DELNKLGDLR KKVEDQLGLN ATFSEEEVRY EIVLEKIRGT
LKERPDEIAM LFKLLIKDEI SSDSAKG
//
