ID T0F300_HELPX Unreviewed; 414 AA.
AC T0F300;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=RNA polymerase sigma54 factor {ECO:0000313|EMBL:EPZ92501.1};
GN ORFNames=N207_02955 {ECO:0000313|EMBL:EPZ92501.1};
OS Helicobacter pylori UM114.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1355531 {ECO:0000313|EMBL:EPZ92501.1, ECO:0000313|Proteomes:UP000015605};
RN [1] {ECO:0000313|EMBL:EPZ92501.1, ECO:0000313|Proteomes:UP000015605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UM114 {ECO:0000313|EMBL:EPZ92501.1,
RC ECO:0000313|Proteomes:UP000015605};
RX PubMed=24051312;
RA Rehvathy V., Tan M.H., Gunaletchumy S.P., Teh X., Wang S., Baybayan P.,
RA Singh S., Ashby M., Kaakoush N.O., Mitchell H.M., Croft L.J., Goh K.L.,
RA Loke M.F., Vadivelu J.;
RT "Multiple genome sequences of Helicobacter pylori strains of diverse
RT disease and antibiotic resistance backgrounds from malaysia.";
RL Genome Announc. 1:E00687-E00713(2013).
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPZ92501.1}.
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DR EMBL; AUSS01000033; EPZ92501.1; -; Genomic_DNA.
DR RefSeq; WP_021310486.1; NZ_AUSS01000033.1.
DR AlphaFoldDB; T0F300; -.
DR PATRIC; fig|1355531.3.peg.1374; -.
DR Proteomes; UP000015605; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 69..247
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 254..408
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
SQ SEQUENCE 414 AA; 48350 MW; D99A8D1E3290D60A CRC64;
MAVLRANLSP KNKLNATLKG WLPILQSELE DLEEVLKQNA LDNPLIKIEN KRIKNFSDRF
SAKNSSDHLE NFATAFKSLF ETLEAQIIPP LFPTETSQKI AMDIISGLNS EGYFEENIEE
RARILEVESE VYEKVRKRFS YLNPAGIGAK DVKESFLFQL ESRELDNNEL YEEVRKIILN
LEKHHEFSKD FYYEKALKIL KSFKNPPAIE FLEKEIEVIP ELFILEVDNE IIVRLNDESY
PTISLEENRF KDSDYLKEKL KEAKDLIDAL NLRKATIYKI GLMLLEYQYD FFKGKKLRPL
KLLDLANEFN HSVSTISRAI SNKYLACERG VFPIKHFFST ALDNSETSNA VIKDYLLELI
KNEDKKEPLS DAKILELIEE KFHLKMVRRT ITKYRQLLNI ASSSERKKLY LMRA
//
