ID T0IGG0_9SPHN Unreviewed; 541 AA.
AC T0IGG0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein {ECO:0000259|PROSITE:PS00624};
GN ORFNames=RLDS_25355 {ECO:0000313|EMBL:EQB10765.1};
OS Sphingobium lactosutens DS20.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1331060 {ECO:0000313|EMBL:EQB10765.1, ECO:0000313|Proteomes:UP000015531};
RN [1] {ECO:0000313|EMBL:EQB10765.1, ECO:0000313|Proteomes:UP000015531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS20 {ECO:0000313|EMBL:EQB10765.1,
RC ECO:0000313|Proteomes:UP000015531};
RX PubMed=24051323;
RA Kumar R., Dwivedi V., Negi V., Khurana J.P., Lal R.;
RT "Draft Genome Sequence of Sphingobium lactosutens Strain DS20T, Isolated
RT from a Hexachlorocyclohexane Dumpsite.";
RL Genome Announc. 1:e00753-13(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB10765.1}.
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DR EMBL; ATDP01000109; EQB10765.1; -; Genomic_DNA.
DR RefSeq; WP_021228508.1; NZ_ATDP01000109.1.
DR AlphaFoldDB; T0IGG0; -.
DR PATRIC; fig|1331060.3.peg.4928; -.
DR eggNOG; COG2303; Bacteria.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000015531; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630}.
FT DOMAIN 257..271
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 95..98
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 222
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 541 AA; 58534 MW; ABB9420953B67FC8 CRC64;
MSDFDYIVIG SGSAGSLMAN RLSADPAIRV ALIEAGPSDR KWPVNLKTAM PVGNIFLLPH
EKYNWKQQLS GNAAIGNRQI NFPRGKLFGG CSAINGGVYI RGQRADYDAW EEAGNVGWSY
DDVLPAFKAV ENYHEGDKPW HGSGGELDVE KPRSFNPIAA AIVDAAVEAG HHRNDDFAGE
RQDGFGRYDL NQRNGTRLSS ARAFLHPALD RPNLTVMADT LVRRILFDRG RAVGLEIEQS
GTRSTISSRR EIILCAGAIN SPQLLLLSGI GPEDHLRAMG IKPVHHLPGV GAHLQDHPTV
HVAMENPSGE SYAVSSKALP RILASPFKYL IKREGMLASN VAECGGFLCT DGSGRPDIQI
TFLVGLKLDA RSVPRRHGYM GLIQLLRPKS AGSVRLASNR PEDKPVIDPN FFADPYDMKT
LIAGFREARR IFAQPALAAM TGNEIEPGAQ HQSDAEIDAA LRKIVNTAYH PTGTCKMGPD
SDPMAVVDGR LRVRGVAGLR VVDASVMPEI ISGNTSAPTM MIAERAARFI LEDAVQSNIA
A
//
