ID T0K2D4_COLGC Unreviewed; 727 AA.
AC T0K2D4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=CGLO_15176 {ECO:0000313|EMBL:EQB45879.1};
OS Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus)
OS (Glomerella cingulata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum gloeosporioides species complex.
OX NCBI_TaxID=1237896 {ECO:0000313|EMBL:EQB45879.1, ECO:0000313|Proteomes:UP000015530};
RN [1] {ECO:0000313|Proteomes:UP000015530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cg-14 {ECO:0000313|Proteomes:UP000015530};
RX PubMed=23902260; DOI=10.1094/MPMI-03-13-0080-R;
RA Alkan N., Meng X., Friedlander G., Reuveni E., Sukno S., Sherman A.,
RA Thon M., Fluhr R., Prusky D.;
RT "Global aspects of pacC regulation of pathogenicity genes in Colletotrichum
RT gloeosporioides as revealed by transcriptome analysis.";
RL Mol. Plant Microbe Interact. 26:1345-1358(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB45879.1}.
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DR EMBL; AMYD01003611; EQB45879.1; -; Genomic_DNA.
DR AlphaFoldDB; T0K2D4; -.
DR STRING; 1237896.T0K2D4; -.
DR eggNOG; KOG1979; Eukaryota.
DR HOGENOM; CLU_004131_2_0_1; -.
DR OMA; ANYHVKK; -.
DR OrthoDB; 5475669at2759; -.
DR Proteomes; UP000015530; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR CDD; cd03483; MutL_Trans_MLH1; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000015530}.
FT DOMAIN 241..360
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 81057 MW; 1526A0013B39940A CRC64;
MDTDSPVGTK RKAEEDPDES RAPRRIRALD PNVVNKIAAG EIIVAPVNAL KELIENAVDA
GATSVEVLVK EGGLKLLQIT DNGCGIQKDD LEILCERHTT SKITSFEDLT SIATYGFRGE
ALASISHIAH LSVTTKTSDS NCAWRAHYLD GKLAPAKPGQ PAEPKPTAGR QGTQISVEDL
FFNVPTRRRA FRSPAEEYNK IIDVVGRYAI HCKGVGFSCK KHGESGTSIS IQALATEVDR
IRQIYGSSVA NELMEFDTSE DRWGFKANGW ATNANYHIKK TTLLLFINHR SVDSNNIKKA
LEQLYATFLP KGGRPFIYLS LEIDPSRVDV NVHPTKREVH FLNEDDIIQS ICEHIRSKLA
EVDTSRTFMT QSLLPGSQLM HISNQEETEG SPSTPDKQTP GFKRPRRNSN NLVRTDTSSR
KITSMLPAAA VAATPSKAPP SAGENALSVS ENIQYEIVDK PFAQMKLTSV KELRAEVRED
MHNDLTEIFA NHTFVGVVDE RRRLAAIQGG VKLYLIDYGR ACFEYCYQVG LTDFGNFGTI
RFTPPLDLRD VLRIGAEMEK NNVESEEEDF EVDVVVEKVA AQLIERREMI GEYFSLEVSP
AGELLSIPLL IKGYTPPMVK LPRFLLRLGP CVNWNDEKPC FELFLKELAT FYVPEQLPPT
IGGAGDNEET ANMDEEIAMR RRNVRWAVEH VFFPAFKARL VATTSMMKAA VLEVADLKGL
YRVFERC
//
