ID T0K6F6_COLGC Unreviewed; 907 AA.
AC T0K6F6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Isochorismatase {ECO:0000313|EMBL:EQB48548.1};
GN ORFNames=CGLO_12234 {ECO:0000313|EMBL:EQB48548.1};
OS Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus)
OS (Glomerella cingulata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum gloeosporioides species complex.
OX NCBI_TaxID=1237896 {ECO:0000313|EMBL:EQB48548.1, ECO:0000313|Proteomes:UP000015530};
RN [1] {ECO:0000313|Proteomes:UP000015530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cg-14 {ECO:0000313|Proteomes:UP000015530};
RX PubMed=23902260; DOI=10.1094/MPMI-03-13-0080-R;
RA Alkan N., Meng X., Friedlander G., Reuveni E., Sukno S., Sherman A.,
RA Thon M., Fluhr R., Prusky D.;
RT "Global aspects of pacC regulation of pathogenicity genes in Colletotrichum
RT gloeosporioides as revealed by transcriptome analysis.";
RL Mol. Plant Microbe Interact. 26:1345-1358(2013).
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQB48548.1}.
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DR EMBL; AMYD01002588; EQB48548.1; -; Genomic_DNA.
DR AlphaFoldDB; T0K6F6; -.
DR STRING; 1237896.T0K6F6; -.
DR eggNOG; ENOG502QRZN; Eukaryota.
DR HOGENOM; CLU_005335_0_0_1; -.
DR OMA; KMYHLSG; -.
DR OrthoDB; 1644896at2759; -.
DR Proteomes; UP000015530; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:InterPro.
DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:InterPro.
DR GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IEA:InterPro.
DR CDD; cd00431; cysteine_hydrolases; 1.
DR CDD; cd00299; GST_C_family; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032854; ALKBH3.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR31212; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR PANTHER; PTHR31212:SF5; ISOCHORISMATASE FAMILY PROTEIN FAMILY (AFU_ORTHOLOGUE AFUA_3G14500); 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR Pfam; PF14497; GST_C_3; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
DR PROSITE; PS50405; GST_CTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015530}.
FT DOMAIN 506..631
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
FT DOMAIN 765..905
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT REGION 288..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 99665 MW; EE40851F3CD3659F CRC64;
MFPFDPSVMP TLPTRKGLLV IDFQNDFLAA DGALPVAEPD ALVSRTLDLV KAFRKTGEII
WVHTEFEKHR PSSAEQILAT DVMPKPTILT SRYRRRPAVQ QESEGPDTDR DLEAFLSQPG
PPVVRPSTSG AQFPAAVKDA IAPRDIKFLK SHYSAFKSGQ LLQMLRFKFV TELFLCGSLA
NVGVHATAVD AVKYGYSITL VEDCCGFISE LRLSNTMRSL VDLTGCDVLE GTAVVEKLQA
KKNPASAASN SSSPVVPKRL RETADDEILV AGDASTPKSQ SLEEKLAGLK LENDVGRPSP
ASRPARSARY RYPDDSECAT ISDMLEVDPD AQPSSSAPII SESLALEVSR NPDAAIQPEE
DTTNGHQIIE AASDDEKTPA SDPELEVDTT IASTETGTMN SDEVDNEDAL KVSEPLCEGD
TTVIYNVIPK PLAEGIFEKV RDEVSWQRMS HQGGEVPRLV AVQGEVAGDG SMPVYRHPSD
ESPPLLSFSP TVREIKTEVE KQLGHQLNHA LIQFYRDGTD YISEHSDKTL DIVKGSHIAN
VSLGAERTMV FRTKRRDKDP SSTESPSGED SKKRQIARAK LPHNSLCRMG LETNMRWLHA
IRQDKRMERD KTPAELAFSG GRISLTFRQI GTFLDRDSTV IWGQGATCKA RDEAKPVING
QSPEAVGMLH AFGTENHSTT FDWDRHYGKG FDVLHMNHSP RLCVSADPVV NTRIALMLAE
YGISYAKGSV SFSFNWKDGE GVNNTSTIPE SPPIRFIDND AVKSTVQGEL AIMMYLDGVY
GSARAEAADK SHSDLARILT RFQQGLALLE KWRQLGRDDE GKRDLKPLNK ELAIWGGYSG
ESEFIAGERI SLADFAVWPV LHTIVEDSGT EALVATGELK EYYERFKNRD STTKVLGTDR
PEGASTP
//
