ID T0MFN5_CAMFR Unreviewed; 1026 AA.
AC T0MFN5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Disks large 4-like protein {ECO:0000313|EMBL:EQB77180.1};
GN ORFNames=CB1_000230007 {ECO:0000313|EMBL:EQB77180.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EQB77180.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EQB77180.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
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DR EMBL; KB016523; EQB77180.1; -; Genomic_DNA.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd03590; CLECT_DC-SIGN_like; 1.
DR CDD; cd00992; PDZ_signaling; 3.
DR CDD; cd12030; SH3_DLG4; 1.
DR Gene3D; 2.30.42.10; -; 3.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR033989; CD209-like_CTLD.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR019583; DLG1-4_PDZ_assoc.
DR InterPro; IPR019590; DLG1_PEST_dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF33; DISKS LARGE HOMOLOG 4; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR Pfam; PF03954; Lectin_N; 1.
DR Pfam; PF10608; MAGUK_N_PEST; 1.
DR Pfam; PF00595; PDZ; 3.
DR Pfam; PF10600; PDZ_assoc; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00034; CLECT; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 3.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1026
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004580915"
FT DOMAIN 81..168
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 176..263
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 329..410
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 444..514
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 550..677
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT DOMAIN 902..1019
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 596..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 804..863
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 596..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..764
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1026 AA; 112823 MW; 2CE0937C2CC39EDB CRC64;
MSARNRFASM CLCVVRAAXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XANSPPVIVN
TDTLEAPGYV NGTEGEMEYE EITLERGNSG LGFSIAGGTD NPHIGDDPSI FITKIIPGGA
AAQDGRLRVN DSILFVNEVD VREVTHSAAV EALKEAGSIV RLYVMRRKPP AEKLMEIKLI
KGPKGLGFSI AGGVGNQHIP GDNSIYVTKI IEGGAAHKDG RLQIGDKILA VNSVGLEDVM
HEDAVAALKN TYDVVYLKVA KPSNAYLSDS YAPPDITTSY SQHLDNEISH SSYLGTDYPT
AMTPTSPRRY SPVAKDLLGE EDIPREPRRI VIHRGSTGLG FNIVGGEDGE GIFISFILAG
GPADLSGELR KGDQILSVNG VDLRNASHEQ AAIALKNAGQ TVTIIAQYKP EEYSRFEAKI
HDLREQLMNS SLGSGTASLR SNPKRGFYIR ALFDYDKTKD CGFLSQALSF RFGDVLHVID
ASDEEWWQAR RVHSDSETDD IGFIPSKRRV ERREWSRLKA KDWGSSSGSQ GREDSVLSYE
TVTQMEVHYA RPIIILGPTK DRANDDLLSE FPDKFGSCVP QRFPSLGRSQ ARRFSEKGAS
QPPSCSTVTI PGQGLGGSGD TTRPKREYEI DGRDYHFVSS REKMEKDIQA HKFIEAGQYN
SHLYGTSVQS VREVAEQASA VASMSRGCHQ LGLVPLLSLS DSGPPGRKAE VLIDAVKRPV
GLELGSNPGA TVADGEGPAG PTMTKEYQDL QHLDNEENDH QHRKGPPPPQ SLFRRLCSGP
RLLLLSMGLS LLLLVVVCVI GSQNSKLQEE LRALRETFSN LTVSTDAQVK ALSIQGGNVG
KKMKSLESQL EKQQQDLSED HSSLLLHVKQ FVADLRSLSC QMAVLQGNGS EGTCCPVNWM
DYEGSCYWFS RSGKPWPEAA KYCELESAHL VVVGSWEEQK FIQHHMGPVN TWMGLTDQNG
PWKWVDGTDY ETGFKNWRPE QPDDWYGHGL GGGEDCAHFT DDGRWNDDVC QRPYRWVCET
KRGRDS
//
