ID T0NR42_CAMFR Unreviewed; 1427 AA.
AC T0NR42;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE SubName: Full=Rho GTPase-activating protein-like protein {ECO:0000313|EMBL:EQB78007.1};
GN ORFNames=CB1_000568033 {ECO:0000313|EMBL:EQB78007.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EQB78007.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EQB78007.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
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DR EMBL; KB016845; EQB78007.1; -; Genomic_DNA.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11835; SH3_ARHGAP32_33; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15729; CDC42 GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15729:SF13; RHO GTPASE-ACTIVATING PROTEIN 32; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 19..81
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 132..321
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 395..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 650..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1019..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1174..1197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1212..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..741
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..765
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..937
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1212..1229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1276..1312
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1427 AA; 154501 MW; 78DE45955AFD6315 CRC64;
MDNKGNHLLV HEESSINTPA VGAAHVIKRY TARAPDELTL EVGDIVSVID MPPKVLSTWW
RGKHGFQVGL FPGHCVELIN QKVPQSVTNS VPKPVSKKHG KLITFLRTFM KSRPTKQKLK
QRGILKERVF GCDLGEHLLN SGFEVPQVLQ SCTAFIERYG IVDGIYRLSG VASNIQRLRH
EFDSEHVPDL TKEPYVQDIH SVGSLCKLYF RELPNPLLTY QLYEKFSDAV SAATDEERLI
KIHDVIQQLP PPHYRSKQIE SACFSGTAAF MEVRIQSVVV EFILNHVDVL FSGRISAAMQ
EGAASLSRPK SLLVPSPSTK LLTLEEAQAR TQAQVTSPAV SENKYIEVGE GPAALQGKFH
TVIEFPLERR RPQNKMKKSP VGSWRSFFNL GKSSSVSKRK LQRNESEPSE MKAAALKGGR
AEGTLRSAKS EESLTSLHAV DGDSKLFRPR RPRSSSDALS ASFNGEMLGN RCNSYDNLPH
DNESEEEVGL LHVPALLSPH SAEDVDLSPP DIGVASLDFD PMSFQCSPPK AESECLEGGA
SFFDSLGYSK DRQNTNNKDS EAGGSQSQTP GSAASSEPVS PVQEKLSPFF TLDLSPTEEK
PSKASSFTEK VVYAFSPKIG RKLSRSPSMN ISEPISVTLP ARVSEVIGTA SNTAAQDAPS
PTWNKSVEES DVINRPPTQV VKLKASEREA QEGCESAAQP LGQVAPAGVE SPGKEEEPAS
ASSGQSKAVP PGQTQTGADN HDPPQDPVPV SSVSLIPPPP PPKNVARLLA LALAESAQQA
STQPPRRPGP SQAACASYGG LAVAAAEDRL PASHSSVTAD RAFFQADMPT EQPHLQDGDQ
PAPGAAAVGD YTHSCATESG GQPHPADFPG SQPHRIYLAG DPEKAGVTSV PLTDSKSDDH
LSFPEDQSAK TSVLTVSFVD QDRSQPRLYS GEQPSSYLGA SVDKPHHPLE LADKSPTPCN
LPRDKVYPPP GSPEEDTSTA PVAYVTTVPT AAEMSTREAG WDVVEQPSAV DFAVATLQRT
HRTSRPLPLP PSQRATEQLP GPGQGQAAAS VGVHNAHKVR RGGSHVVSMP PVADVKHSYT
SWDLEDMEKY RVQSIRRESR ARQKVKGPVV SQYDNMAPAA QDDLGGIYVI HLRSKSDPGK
TGLLSVAEGK EGRHAVKAVS PEGEDRFYRK HAEPELDRAH PHGAYGGGQP EKPCLPQKQS
SLRNRKLHDM GCGLPEHRGH QEASHRQLCE SKHGPPYPQG AGQLDYGPQG IPDASEPVSY
HNSGGIYVPS GQESLRLNHK EVRLSKELER PRARQPPAPE KHSRDGYKEE EHLAPSVVPP
PKPERSHSLK LHHAQSVERD AGVLYQYQPH GKRQGGVTMV PQYDNLEGYH SPPQLQRGAF
GAAALGVYVP PGFAHPQSRT YATALGQGAF LPAELALQHP ETQIHAE
//
