ID T0PPW4_AERSA Unreviewed; 327 AA.
AC T0PPW4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=RNA polymerase sigma factor RpoS {ECO:0000256|HAMAP-Rule:MF_00959};
DE AltName: Full=Sigma S {ECO:0000256|HAMAP-Rule:MF_00959};
DE AltName: Full=Sigma-38 {ECO:0000256|HAMAP-Rule:MF_00959};
GN Name=rpoS {ECO:0000256|HAMAP-Rule:MF_00959,
GN ECO:0000313|EMBL:ATP07975.1};
GN ORFNames=Asalp_07270 {ECO:0000313|EMBL:ATP07975.1};
OS Aeromonas salmonicida subsp. pectinolytica 34mel.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=1324960 {ECO:0000313|EMBL:ATP07975.1, ECO:0000313|Proteomes:UP000222916};
RN [1] {ECO:0000313|Proteomes:UP000222916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=34mel {ECO:0000313|Proteomes:UP000222916};
RX PubMed=29304740; DOI=10.1186/s12864-017-4301-6;
RA Pfeiffer F., Zamora-Lagos M.A., Blettinger M., Yeroslaviz A., Dahl A.,
RA Gruber S., Habermann B.H.;
RT "The complete and fully assembled genome sequence of Aeromonas salmonicida
RT subsp. pectinolytica and its comparative analysis with other Aeromonas
RT species: investigation of the mobilome in environmental and pathogenic
RT strains.";
RL BMC Genomics 19:20-20(2018).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. This sigma factor is the master transcriptional regulator of
CC the stationary phase and the general stress response.
CC {ECO:0000256|HAMAP-Rule:MF_00959}.
CC -!- SUBUNIT: Interacts with the RNA polymerase core enzyme.
CC {ECO:0000256|HAMAP-Rule:MF_00959}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00959}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoS subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_00959}.
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DR EMBL; CP022426; ATP07975.1; -; Genomic_DNA.
DR RefSeq; WP_017411567.1; NZ_CP022426.1.
DR AlphaFoldDB; T0PPW4; -.
DR GeneID; 79881220; -.
DR OrthoDB; 9809557at2; -.
DR Proteomes; UP000222916; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR HAMAP; MF_00959; Sigma70_RpoS; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR012761; RNA_pol_sigma_RpoS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02394; rpoS_proteo; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR PANTHER; PTHR30603:SF67; RNA POLYMERASE SIGMA FACTOR RPOS; 1.
DR Pfam; PF00140; Sigma70_r1_2; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00959};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00959};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082, ECO:0000256|HAMAP-
KW Rule:MF_00959};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00959};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00959}.
FT DOMAIN 114..127
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 283..309
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT DNA_BIND 284..303
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959"
FT REGION 52..85
FT /note="Sigma-70 factor domain-1"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959"
FT REGION 90..160
FT /note="Sigma-70 factor domain-2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959"
FT REGION 170..245
FT /note="Sigma-70 factor domain-3"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959"
FT REGION 258..311
FT /note="Sigma-70 factor domain-4"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959"
FT MOTIF 114..117
FT /note="Interaction with polymerase core subunit RpoC"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959"
SQ SEQUENCE 327 AA; 37733 MW; 4ED0FB03715A0155 CRC64;
MSQEQLVMQD AELEFDEELE TREEEEVQEV AAEVEETISD ELMAPEVNKV MDATQLYLGE
IGFSPLLTAE EEVYYARRAL RGDKAARKRM IESNLRLVVK IARRYNNRGL VLLDLIEEGN
LGLIRAVEKF DPERGFRFST YATWWIRQTI ERAIMNQTRT IRLPIHVVKE LNVYLRTARE
LSHRLDHEPT AEDIAFALDR SVDDVNRMLK LNEKITSVDT PIGGDRDKAL LDVLSDERGM
GPELESQDDD MRASIVHWLE ELNPKQREVL ARRFGLLGYE PATLEDVGSE IGLTRERVRQ
IQVEGLRRLR EILLGQGLSI EALFRTN
//
