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Database: UniProt
Entry: T0SCR8_9DELT
LinkDB: T0SCR8_9DELT
Original site: T0SCR8_9DELT 
ID   T0SCR8_9DELT            Unreviewed;       514 AA.
AC   T0SCR8;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   05-JUL-2017, entry version 29.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:EQC43333.1};
GN   ORFNames=M900_0001 {ECO:0000313|EMBL:EQC43333.1};
OS   Bacteriovorax sp. Seq25_V.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Bdellovibrionales;
OC   Bacteriovoracaceae; Bacteriovorax.
OX   NCBI_TaxID=1201288 {ECO:0000313|EMBL:EQC43333.1, ECO:0000313|Proteomes:UP000015895};
RN   [1] {ECO:0000313|EMBL:EQC43333.1, ECO:0000313|Proteomes:UP000015895}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SEQ25_V {ECO:0000313|Proteomes:UP000015895};
RA   Chen H., Brinkac L.M., Mishra P., Dickerson T., Gordon-Bradley N.,
RA   Lymperopoulou D.S., Williams H.N., Badger J.H.;
RT   "Draft Genome Sequences for the obligate bacterial predators
RT   Bacteriovorax spp. of four phylogenetic clusters.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EQC43333.1}.
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DR   EMBL; AUNI01000021; EQC43333.1; -; Genomic_DNA.
DR   EnsemblBacteria; EQC43333; EQC43333; M900_0001.
DR   PATRIC; fig|1201288.3.peg.3038; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000015895; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000015895};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015895}.
FT   DOMAIN      212    342       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      424    493       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     220    227       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   514 AA;  58198 MW;  673F36C9E5450436 CRC64;
     MQGNFPFSQF LKSGNSINNF DHLSNIPVST PTNNQELIGD FDVEEIEMMN QEIHKVLQNS
     VTTQKYTAFF EGSFNLKTIN QGTAIFTVPT QFIKSMVEKN LPQISESIFS ILGKQYQIDI
     SVEGTADQQT APIEPPKARS AAEVSFKLDL EPKKEDLLSK VESKYIDHIN PEHTGILIDP
     VKKFTNFVVG PSNNMAYAAA LAIAKHPGKA GKYPSLYIHS NSGLGKTHLL HAIANGAKEN
     YPHFIICLIT ARDFMREMID AIKAEQLHEF RKKYSEKVDI LMIDDVHELK GREGTQREFF
     HIFNELYNKG KQLIFTSDKT PQEINGLEER IRTRLQWGLV VDIQKPDFET RTAIIKTKAD
     ELDLFLSDDI INLIACNVKN SIRELEGSLI KLSAYTDIMK VDIDIEMVKD VLALKEHEDE
     RKVTLEIVAK TTSHHFRIPI ADLKSKSRTK DIANARFIAM YLSRKIVGAT HEEIGKFYGG
     RDHSSVVHAE QKITKQLSSD SQLSRDVMTI ENSL
//
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