ID   T0TCM3_9STRE            Unreviewed;       202 AA.
AC   T0TCM3;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN   ORFNames=HSISB1_1954 {ECO:0000313|EMBL:EQC68836.1};
OS   Streptococcus sp. HSISB1.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1316409 {ECO:0000313|EMBL:EQC68836.1};
RN   [1] {ECO:0000313|EMBL:EQC68836.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HSISB1 {ECO:0000313|EMBL:EQC68836.1};
RA   Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA   Kleerebezem M.;
RT   "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT   Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL   PLoS ONE 8:E83418-E83418(2013).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC       {ECO:0000256|RuleBase:RU366058}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU366058}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQC68836.1}.
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DR   EMBL; ASKA01000035; EQC68836.1; -; Genomic_DNA.
DR   AlphaFoldDB; T0TCM3; -.
DR   PATRIC; fig|1316409.3.peg.1439; -.
DR   HOGENOM; CLU_038944_5_2_9; -.
DR   Proteomes; UP000015934; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR015414; TMEM64.
DR   InterPro; IPR032816; VTT_dom.
DR   PANTHER; PTHR12677:SF55; TVP38_TMEM64 FAMILY MEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU366058};
KW   Membrane {ECO:0000256|RuleBase:RU366058};
KW   Transmembrane {ECO:0000256|RuleBase:RU366058};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   TRANSMEM        89..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366058"
FT   DOMAIN          70..192
FT                   /note="VTT"
FT                   /evidence="ECO:0000259|Pfam:PF09335"
SQ   SEQUENCE   202 AA;  22548 MW;  931D5960E7EC1975 CRC64;
     MTVAGTQRKY IQILTGIGFA ISVGLFIFFK QHPTYFQVGG LFQSYLGNLG LFAPLIFMAL
     QMIQVIYPIV PGGMTSVIGY LAFGPIWGFV YNFTGIFIGS LLAFGLARRY GESFAKAFVS
     QETYDKYIGY LDKNDGKYFA KLLGAAFALP GFPDDFLCMV SGLSKMTWKK FITIFLITKP
     VTLYLYTVIG YQGLSFLLTL FK
//