ID T0TYM8_9STRE Unreviewed; 700 AA.
AC T0TYM8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Gram-positive cocci surface proteins LPxTG domain-containing protein {ECO:0000259|PROSITE:PS50847};
GN ORFNames=HSISM1_258 {ECO:0000313|EMBL:EQC75937.1};
OS Streptococcus sp. HSISM1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1316408 {ECO:0000313|EMBL:EQC75937.1};
RN [1] {ECO:0000313|EMBL:EQC75937.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSISM1 {ECO:0000313|EMBL:EQC75937.1};
RA Van den Bogert B., Boekhorst J., Herrmann R., Smid E.J., Zoetendal E.G.,
RA Kleerebezem M.;
RT "Comparative Genomics Analysis of Streptococcus Isolates from the Human
RT Small Intestine Reveals their Adaptation to a Highly Dynamic Ecosystem.";
RL PLoS ONE 8:E83418-E83418(2013).
CC -!- SIMILARITY: Belongs to the serine-aspartate repeat-containing protein
CC (SDr) family. {ECO:0000256|ARBA:ARBA00007257}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQC75937.1}.
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DR EMBL; ASKI01000081; EQC75937.1; -; Genomic_DNA.
DR AlphaFoldDB; T0TYM8; -.
DR PATRIC; fig|1316408.3.peg.1874; -.
DR eggNOG; COG4932; Bacteria.
DR HOGENOM; CLU_002287_3_0_9; -.
DR Proteomes; UP000015933; Chromosome.
DR Gene3D; 2.60.40.3050; -; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR022464; Strep_pil_isopept_link.
DR InterPro; IPR038174; Strep_pil_link_sf.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR03786; strep_pil_rpt; 2.
DR PANTHER; PTHR36108:SF13; COLOSSIN-B; 1.
DR PANTHER; PTHR36108; COLOSSIN-B-RELATED; 1.
DR Pfam; PF12892; FctA; 2.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17802; SpaA; 3.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512}.
FT DOMAIN 668..700
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 610..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..649
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 700 AA; 74628 MW; 241CBF075A1030A1 CRC64;
MVNVEDFGAD HSVTKTIINP KDKPKETKAT IELDKALTGR DLKDGEFSFE LYEGATKLQT
VTNKNGKVTF DPISYKEAGE HTYTVKEVVG NTPGITYDTT EKQVTVKVTQ DGQALKADLV
YPENKTFNNT YTAPQPAKAK ISASKILEGA ELKNGEFNFQ LLDETGKVLQ TKQNAADGTV
TFDDISYSSE DAGKTFHYTI KEVIPESKTK GMTYDEGSID ATVTVTKDDA SNTLKASVAY
GDKKSFTNKL VTTSIPPTPP TVDKPELKLY SIQLHKVNQE GKALAGAVFG LFEADGTTPV
ANPYGEGQAT ATSSDEEGKK GLVTFIGLEA KDYVVKELTA PEGYQLSTDV IKVSTSELKA
ATNLVVDKGT VVNKPFTSIP PTPPTVDKPE LKLYSIQLHK VNQEGKALVG AVFGLFEADG
TTPVANPYGE GQATATSDAN GLVTFTGLEA KDYVVRELTA PDGYQLSDEV IKIAASDLVA
SNNVVDKGNV VNKPFTSIPP TPPTVDKPEL KLYNIQLHKV SEEGKGLLGA VFGLYEADGT
TPVANPYGEG QATATSDENG LVTFIGFEAK DYVIKELTAP TGYQLLTNPI TVSASDFTQA
KDLVVDKGNV VNNKIPPYTP PYTPPYTPPT PPTTPPTTPS TPPTPSTDKP KGNQPSGKQS
KEGKKQSLPS TGETVSAGFI TAGLVLASAG SMLVAKKRHE
//
