ID   T1A011_9ZZZZ            Unreviewed;       335 AA.
AC   T1A011;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Tyrosine decarboxylase {ECO:0000313|EMBL:EQD53896.1};
DE   Flags: Fragment;
GN   ORFNames=B1B_09967 {ECO:0000313|EMBL:EQD53896.1};
OS   mine drainage metagenome.
OC   unclassified sequences; metagenomes; ecological metagenomes.
OX   NCBI_TaxID=410659 {ECO:0000313|EMBL:EQD53896.1};
RN   [1] {ECO:0000313|EMBL:EQD53896.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Mendez C., Richter M., Ferrer M., Sanchez J.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EQD53896.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24430486; DOI=10.1038/ismej.2013.242;
RA   Mendez-Garcia C., Mesa V., Sprenger R.R., Richter M., Diez M.S., Solano J.,
RA   Bargiela R., Golyshina O.V., Manteca A., Ramos J.L., Gallego J.R.,
RA   Llorente I., Martins Dos Santos V.A., Jensen O.N., Pelaez A.I., Sanchez J.,
RA   Ferrer M.;
RT   "Microbial stratification in low pH oxic and suboxic macroscopic growths
RT   along an acid mine drainage.";
RL   ISME J. 8:1259-1274(2014).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EQD53896.1}.
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DR   EMBL; AUZY01006579; EQD53896.1; -; Genomic_DNA.
DR   AlphaFoldDB; T1A011; -.
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR021115; Pyridoxal-P_BS.
DR   InterPro; IPR049373; TyrDC_C.
DR   PANTHER; PTHR42735; -; 1.
DR   PANTHER; PTHR42735:SF4; TYROSINE DECARBOXYLASE; 1.
DR   Pfam; PF21391; tyr_de_CO2_C; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00392; DDC_GAD_HDC_YDC; 1.
PE   4: Predicted;
FT   DOMAIN          164..293
FT                   /note="L-tyrosine decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21391"
FT   REGION          312..335
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EQD53896.1"
SQ   SEQUENCE   335 AA;  37305 MW;  2515D7248FD0D262 CRC64;
     VRLREEYARR GVSFYLHVDA AFGGYGAALF RDESGRFLAY EELQGRMAEL GLDRWGKDLP
     SRTVWAAYRA LSDVDSVTID PHKMGYVPYS AGGIALRDRR ILGLVSYSAA YVFDAANPLD
     MNLGSVILEG SKAGATAAAV WAAHRLVPLD IRGYGQIVAR SIGGAYHFIK TLESMHEFVA
     GGQKIVCEPL LAQPDFNVVC MAYNFKGNSS LRKMNRLNEA IYHESSYESG PLYNDEWITS
     HTVLDKEIYG DAPKSFLDRL GIGPKEWDRI GSVNVLRSVV MHPWIANNST YPERWESYLS
     IVKKDIDRIV SHSRGRAGKD GRRGHGPKLR GPETT
//