ID T1CQ52_9HELI Unreviewed; 675 AA.
AC T1CQ52;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=HFN_0010 {ECO:0000313|EMBL:GAD18879.1};
OS Helicobacter fennelliae MRY12-0050.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1325130 {ECO:0000313|EMBL:GAD18879.1, ECO:0000313|Proteomes:UP000018143};
RN [1] {ECO:0000313|EMBL:GAD18879.1, ECO:0000313|Proteomes:UP000018143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRY12-0050 {ECO:0000313|EMBL:GAD18879.1,
RC ECO:0000313|Proteomes:UP000018143};
RA Rimbara E., Matsui M., Mori S., Suzuki S., Suzuki M., Kim H., Sekizuka T.,
RA Kuroda M., Shibayama K.;
RT "Draft Genome Sequence of Helicobacter fennelliae Strain MRY12-0050,
RT Isolated from a Bacteremia Patient.";
RL Genome Announc. 1:e00512-13(2013).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD18879.1}.
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DR EMBL; BASD01000010; GAD18879.1; -; Genomic_DNA.
DR RefSeq; WP_023947848.1; NZ_BASD01000010.1.
DR AlphaFoldDB; T1CQ52; -.
DR STRING; 1325130.HFN_0010; -.
DR eggNOG; COG1345; Bacteria.
DR OrthoDB; 1530at2; -.
DR Proteomes; UP000018143; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:GAD18879.1};
KW Cilium {ECO:0000313|EMBL:GAD18879.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:GAD18879.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018143};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 13..108
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 424..658
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 675 AA; 73330 MW; FA3D3830E9D2848C CRC64;
MAIGKINSLG VGSGVLNYDV IDKLRESDEK AMIKPIERKM EQNVEKQKTL AEIKTLLSGL
RTPTKFLADY SSYLGRTTHV NSDAIKASVA SGVPIQDIKI DVHQLAQGDI NEIGGKFESR
DSTFSENDIK LSFFTQGKKY DINIKAGMSV GDVAQLITDE TNGEVTGIIM KTGGAKPYQL
MLNSKGMGDQ SRIYFGTLMQ TGVIQNGALN LEQGDFNITL KDNHGNEHTL DIILKTDGSS
DSALVLKEAI KEAIQKNTDL KDLLDSDINI GLDNDGKSLI LNDLRGYEIK VGGNQAKALG
FKETQSKQEP LAQSGSAVKA GKLSGVVQIG SVPLDLAKMT KDKNTSEQNA QIIAQAIENI
AGMHAKTDGQ GKLTLYSEIG EIKIQANDDV GKQAIADMGL QAGIMQGYAK LQDSLFKIKN
IQKGSDALIS YNGALVSRPT NEINDVISGV SLTLQSTTEE GKPAIISVGR DTQAIVDNLK
EFVKAYNELV PKLNESTRYD EDSKIAGIFN GVSDIRTIRS SLNSLITYSE FLDTNILNLV
AYGITLNDNG VMFLDENKLS SAINSNPKGT EEFFFGKDKK ESSGKETHID GVFVKIDKFL
SGLVDGSNSR LEVFGSSLER DAKSLQKDKK SANELLDTRY DTMAQRFAAY DNQIAKTKNA
FGSVQMMIDQ SVAKK
//
