ID   T1E7J3_ANOAQ            Unreviewed;       340 AA.
AC   T1E7J3;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha {ECO:0000256|ARBA:ARBA00040965};
DE            EC=2.5.1.58 {ECO:0000256|ARBA:ARBA00012702};
DE            EC=2.5.1.59 {ECO:0000256|ARBA:ARBA00012700};
DE   AltName: Full=CAAX farnesyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043086};
DE   AltName: Full=FTase-alpha {ECO:0000256|ARBA:ARBA00042436};
DE   AltName: Full=Ras proteins prenyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00041392};
DE   AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043219};
OS   Anopheles aquasalis (Malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=42839 {ECO:0000313|EMBL:JAA98598.1};
RN   [1] {ECO:0000313|EMBL:JAA98598.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole body {ECO:0000313|EMBL:JAA98598.1};
RG   Brazilian Malaria Network (MCT/CNPq/MS/SCTIE/DECIT/PRONEX 555648/2009-5) and Research Network on Bioactive Molecules from Arthropod Vectors (NAP-MOBIARVE;
RG   University of Sao Paulo);
RA   Marinotti O., Ribeiro J.M.C., Costa-da-Silva A.L., Silva M.C.P.,
RA   Lopes A.R., Barros M.S., Sa-Nunes A., Konjin B.B., Carvalho E., Suesdek L.,
RA   Silva-Neto M.A.C., Capurro M.L.;
RT   "Transcriptome sequencing and developmental regulation of gene expression
RT   in Anopheles aquasalis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC       family. {ECO:0000256|ARBA:ARBA00006734}.
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DR   EMBL; GAMD01002992; JAA98598.1; -; mRNA.
DR   VEuPathDB; VectorBase:AAQUA_011573; -.
DR   GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR   Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR   InterPro; IPR002088; Prenyl_trans_a.
DR   PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR   PANTHER; PTHR11129:SF1; PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA; 1.
DR   Pfam; PF01239; PPTA; 4.
DR   SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR   PROSITE; PS51147; PFTA; 4.
PE   2: Evidence at transcript level;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022602}.
SQ   SEQUENCE   340 AA;  39861 MW;  9FF9CEA0179FC900 CRC64;
     MADGNSSDED FSDDWVLYAQ RPGWADIEPL PQDDGENPVV MIQYSEKFND VFGYLRAIIS
     RQEKSERALE LTKDAAKLNA ANYTVWQYRR DILKDLNADL YEELSYIGKV IAEXXXXYQV
     WHHRRVIVEW LDDPSSELAL TESILDMDAK NYHAWQHRQW VIKKYNLFDD ELQYVDRLIS
     EDMRNNSAWN ERFFVLKHGG FTQEVLEREI NYVMTRVGLI KNNESPWNFL RGLLQQGTGK
     LTQFPSVIDF CEDLYNDGIR SPYLLAFLVD LYEERYFEVL SSTGGNVDEA DEYRAKVQDL
     CESMANQHDK IRCKYWRYIA DSFRRKAEAR TAADGGRNGV
//