ID T1EAK6_ANOAQ Unreviewed; 665 AA.
AC T1EAK6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Putative vesicle coat complex copii subunit sfb3 {ECO:0000313|EMBL:JAB01264.1};
DE Flags: Fragment;
OS Anopheles aquasalis (Malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=42839 {ECO:0000313|EMBL:JAB01264.1};
RN [1] {ECO:0000313|EMBL:JAB01264.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Whole body {ECO:0000313|EMBL:JAB01264.1};
RG Brazilian Malaria Network (MCT/CNPq/MS/SCTIE/DECIT/PRONEX 555648/2009-5) and Research Network on Bioactive Molecules from Arthropod Vectors (NAP-MOBIARVE;
RG University of Sao Paulo);
RA Marinotti O., Ribeiro J.M.C., Costa-da-Silva A.L., Silva M.C.P.,
RA Lopes A.R., Barros M.S., Sa-Nunes A., Konjin B.B., Carvalho E., Suesdek L.,
RA Silva-Neto M.A.C., Capurro M.L.;
RT "Transcriptome sequencing and developmental regulation of gene expression
RT in Anopheles aquasalis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; GAMD01000327; JAB01264.1; -; mRNA.
DR AlphaFoldDB; T1EAK6; -.
DR VEuPathDB; VectorBase:AAQUA_010912; -.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF39; SECRETORY 24AB, ISOFORM A; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 2: Evidence at transcript level;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329}.
FT DOMAIN 72..305
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 314..398
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 409..510
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 540..592
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB01264.1"
SQ SEQUENCE 665 AA; 74694 MW; 19DBF9DA6785E5C4 CRC64;
PLSFLPDLHQ SVCLFVDSKK WKCNLCYRVN ELPEEFQYDP VTKTYGDPTR RPEIKSSTIE
FIAPSEYMLR PPQPAIYLFL LDVSSLAQQS GYLHTVCNTL TEHLENLPGD ARTQVGFIAY
NSAIHFYNIA EGFNQPHEVT VLDVEDVFLP YPDNLLVNLK ECKELIKDLL KQLPKRFEHT
HDTHSALGAA LQVAFKMMTA SGGRVTVFQT CLPNHGPGAL QSREDPNNRS SKDVAHLGPA
TDFYKRLALE CSGQQIAVDL FLLNSQYCDL ATISGISKFS GGCLHHIPLY SESKPQLVKT
LRKCFERYLT RKVGFEAVMR VRCTRGLAIH TFHGNFFVRS TDLLSLPNVN PDAGFGMQIT
YEESLAECKS VCFQAALLYT SSKAERRIRV HTLCIPVTAS LTEVMYSADA QCIVGLLSKM
AVDRSLSSSL SDARDAFINA TVDIFSAFKI AQNLPQNSST IVAPENLSLL PLYILALLKH
PAFRTGTSTR LDDRVFAMCE MKSLPLDQLI RYIYPEFYVL DCLFVTPGAG GYVDDGHKLE
PPRLQLSAEK LDSRSMFLLD CGSYMFIYIG SNVASSIVQD ILGYNSVSEI PDFCIDLPSR
ETAASEALLT FLDSINEEKP YTSYVQVIRD TSQFRSMLVE KFVDDRNPNS LAYYEFLQHL
RTQIK
//
