ID T1ER62_HELRO Unreviewed; 325 AA.
AC T1ER62;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN Name=20199062 {ECO:0000313|EnsemblMetazoa:HelroP161161};
GN ORFNames=HELRODRAFT_161161 {ECO:0000313|EMBL:ESO01953.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP161161, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO01953.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP161161}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01000758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096742; ESO01953.1; -; Genomic_DNA.
DR RefSeq; XP_009019361.1; XM_009021113.1.
DR AlphaFoldDB; T1ER62; -.
DR STRING; 6412.T1ER62; -.
DR EnsemblMetazoa; HelroT161161; HelroP161161; HelroG161161.
DR GeneID; 20199062; -.
DR KEGG; hro:HELRODRAFT_161161; -.
DR CTD; 20199062; -.
DR eggNOG; KOG2301; Eukaryota.
DR HOGENOM; CLU_074210_0_0_1; -.
DR InParanoid; T1ER62; -.
DR OMA; CNDESKR; -.
DR OrthoDB; 1110761at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR45628:SF7; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..291
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 325 AA; 37626 MW; EE4095AABBD416A2 CRC64;
MIVISASSVA LAAEDPVFEN SERNRILNHF DYVFTGVFTV EMILKTKLYD LTHSPLAHWQ
IINLGVIFHP GAYCRDLWNI LDALVVVCAL VAFAFTDSPS AGKNLNTIKS LRVLRVLRPL
KTINRVPKLK AVFDCVVNSL KNVFNIMIVY LLFQFIFAVI AVQLFKGRFF FCNDDSKNTR
ETCRGYYFEY EIEGNEQPTI RVEKRKWDKR EFHYDNVAFA MLTLFAVQTG EGWPLVLKNS
IEATFEDRGP QPGFRMEMAI FYIVYFIVFP FFFINIFVAL IIITFQEQGE NELIDQELDK
NQVGLNFCLI FFVTFCDLAC ENLCF
//
