ID T1FNZ0_HELRO Unreviewed; 562 AA.
AC T1FNZ0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
GN Name=20210537 {ECO:0000313|EnsemblMetazoa:HelroP186384};
GN ORFNames=HELRODRAFT_186384 {ECO:0000313|EMBL:ESO06389.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP186384, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO06389.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP186384}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01000621; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096324; ESO06389.1; -; Genomic_DNA.
DR RefSeq; XP_009015757.1; XM_009017509.1.
DR AlphaFoldDB; T1FNZ0; -.
DR STRING; 6412.T1FNZ0; -.
DR EnsemblMetazoa; HelroT186384; HelroP186384; HelroG186384.
DR GeneID; 20210537; -.
DR KEGG; hro:HELRODRAFT_186384; -.
DR CTD; 20210537; -.
DR eggNOG; KOG4441; Eukaryota.
DR HOGENOM; CLU_004253_14_3_1; -.
DR InParanoid; T1FNZ0; -.
DR OMA; EKFPVHR; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 4.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 14..81
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 562 AA; 63621 MW; 92CAD5722CF83D1A CRC64;
MQGLNKLKRE KVLCDVTLIA EGERFEVHKI ILVSCSDYFR SMFTSGMKEC TQKEIELKGI
TSKGLEKVLE IIYTSTTYLE GDDIFDVIAA ATHLQVTPVI EFCERNFLSG MTTSNYYDFI
NTARLYSMSS ALRQIDTFIC KNLLQISKDG TLHLLTYEQI NACLNYGSLS LKEIDIFQVV
WDWLKLDSAQ DLHSIPLMKC IRHVQAVDIM MKHVELRDMV VWALNYHVVP HSQPIKANPS
ITTLRTYSER LVSIGGREIH PNPGLHDEIW AVNDDVINPS TLLNCRRRIT TLPTPLSHMQ
VVAFNDFLYV IGGCTTQCAH GESAVNSVVR YDPRFNVWFQ VANMINKRAY FYAGLLKNRI
IAVGGKFKEG SLSAVELYDP ERNVWVQGPS LPFCYHAHAG AVHKGRVYVS GGYSSNHFTP
DLLRLDVFTG VWDELSPMSY PRGWHVMCVV RDRILVFGGC NLNANQHALP VMQSESYDPD
IDQWTNITPL SVSHKEASCV LYRDKVYVLG GYNVQTKTGQ KSVSRYDPYS AVWECVGSLS
QSHTGVGYCV LKLPKFENHP LD
//
