ID T1FWE4_HELRO Unreviewed; 359 AA.
AC T1FWE4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=SP-RING-type domain-containing protein {ECO:0000259|PROSITE:PS51044};
GN Name=20213139 {ECO:0000313|EnsemblMetazoa:HelroP194780};
GN ORFNames=HELRODRAFT_194780 {ECO:0000313|EMBL:ESN89878.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP194780, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN89878.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP194780}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01008567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097795; ESN89878.1; -; Genomic_DNA.
DR RefSeq; XP_009032043.1; XM_009033795.1.
DR AlphaFoldDB; T1FWE4; -.
DR STRING; 6412.T1FWE4; -.
DR EnsemblMetazoa; HelroT194780; HelroP194780; HelroG194780.
DR GeneID; 20213139; -.
DR KEGG; hro:HELRODRAFT_194780; -.
DR CTD; 20213139; -.
DR eggNOG; KOG2169; Eukaryota.
DR HOGENOM; CLU_772292_0_0_1; -.
DR InParanoid; T1FWE4; -.
DR OrthoDB; 20246at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF104; TONALLI, ISOFORM E; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 89..170
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 69..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 39536 MW; BB6B05083315EBB5 CRC64;
MSLKERSLHR PLYLKDVCIP GRNTIQITVS ACCCSHLFVL QLVHRPSMKS VLQGLLRKRM
LPADHCITKK EQSSTNSSLS PPLPTSSSSS SSLTPEHIKL HLRCPITSQQ IVLPARGHDC
KHIQCFDLES YLQFNCERSL WRCPVCNKPA LLEGLEVDQY MWSIINNLQG CNYDEVLIDH
TASWRPVMLL PPAAAAVGAA AKIEEDKQWT KTVSPSSMIM SSWQPQAGNN YPTSQADSHE
TLKTPDIKDE FNTEIGFHTS SLIEGSCVPD DGDDNDLDLL PVALTDPTEL LSYLGPNLAE
DGHSGSNSSA DNNNNITASN ASSDINSFVD FIDGNVNNNN SSDNNNSNCF NDDLLMLFS
//
