ID T1FXW7_HELRO Unreviewed; 215 AA.
AC T1FXW7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Methyltransferase small domain-containing protein {ECO:0000259|Pfam:PF05175};
GN Name=20213665 {ECO:0000313|EnsemblMetazoa:HelroP64578};
GN ORFNames=HELRODRAFT_64578 {ECO:0000313|EMBL:ESO05908.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP64578, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO05908.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP64578}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic/archaeal PrmC-related family.
CC {ECO:0000256|ARBA:ARBA00006149}.
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DR EMBL; AMQM01000462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096324; ESO05908.1; -; Genomic_DNA.
DR RefSeq; XP_009015276.1; XM_009017028.1.
DR AlphaFoldDB; T1FXW7; -.
DR STRING; 6412.T1FXW7; -.
DR EnsemblMetazoa; HelroT64578; HelroP64578; HelroG64578.
DR GeneID; 20213665; -.
DR KEGG; hro:HELRODRAFT_64578; -.
DR CTD; 20213665; -.
DR eggNOG; KOG3191; Eukaryota.
DR HOGENOM; CLU_018398_6_0_1; -.
DR InParanoid; T1FXW7; -.
DR OMA; EWDDWME; -.
DR OrthoDB; 124743at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0035657; C:eRF1 methyltransferase complex; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008276; F:protein methyltransferase activity; IBA:GO_Central.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR004557; PrmC-related.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR00537; hemK_rel_arch; 1.
DR PANTHER; PTHR45875; METHYLTRANSFERASE N6AMT1; 1.
DR PANTHER; PTHR45875:SF1; METHYLTRANSFERASE N6AMT1; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 28..128
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 215 AA; 23736 MW; 66984A5DAAD7BA3F CRC64;
MASRATPNLI LGGEEFKDVY EPAEDTFLLL DALEKDELQI KSIQPLICLE VGSGSGCVSS
FVAAMLGSAT FYICTDINKK ATLMTKTTGI INGNQQLNPV LTNFADALDK RLSRSVDLLI
FNPPYVVTDS LEVKYPDIIS KSWAGGIKGR EVLDKFLPRV ENLLSHQGVF YLVAIKPNKP
DEIVGIMSSY GFTCSTVMER RAGIEHLLIL KFKRK
//
