ID T1G045_HELRO Unreviewed; 361 AA.
AC T1G045;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN Name=20214443 {ECO:0000313|EnsemblMetazoa:HelroP70316};
GN ORFNames=HELRODRAFT_70316 {ECO:0000313|EMBL:ESN91756.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP70316, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN91756.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP70316}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01002186; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097700; ESN91756.1; -; Genomic_DNA.
DR RefSeq; XP_009030114.1; XM_009031866.1.
DR AlphaFoldDB; T1G045; -.
DR STRING; 6412.T1G045; -.
DR EnsemblMetazoa; HelroT70316; HelroP70316; HelroG70316.
DR GeneID; 20214443; -.
DR KEGG; hro:HELRODRAFT_70316; -.
DR CTD; 20214443; -.
DR eggNOG; KOG4211; Eukaryota.
DR HOGENOM; CLU_032003_1_0_1; -.
DR InParanoid; T1G045; -.
DR OMA; SACKIQN; -.
DR OrthoDB; 2967733at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0043484; P:regulation of RNA splicing; IBA:GO_Central.
DR CDD; cd12504; RRM2_hnRNPH_CRSF1_like; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13976:SF76; AT27789P; 1.
DR PANTHER; PTHR13976; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 6..83
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 276..361
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 361 AA; 40192 MW; 5856DD683A6FE3A0 CRC64;
MSETDFIVRL RGLPWSADSA EIVRFLEDCK LTEENVHIIR LYDGRSTGEA YVELSSEEDV
NKAIAKNKKH LGKRYVDVHK AKRSEMEFAL KRTNQSVPMN GKSKNVPIVK LRGLPFSCSK
EEVANFFSGL EIAPNGITFI TDHLGRCTGE GYVQFISQES IEKALTKHKQ AIAHRYIEVF
QCSVEDLSAA LNRGYMGGRG GYYQHSYQNN KPNRFQKGYR GGYGRGGYYP MANGGFQYGG
GGGGYYGNQS NFRGGKRPFI GGYKFKPTFH ESSTGHSIFM KGLPFAATDK DIAGFFEPLS
LVDVKIHLNH SGRPSGNASV DFQSHEDALE AMKKNKNILG TFILLPTNFL INHATALLIE
L
//
