ID T1G1Z7_HELRO Unreviewed; 383 AA.
AC T1G1Z7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Junctophilin {ECO:0008006|Google:ProtNLM};
GN Name=20215095 {ECO:0000313|EnsemblMetazoa:HelroP75040};
GN ORFNames=HELRODRAFT_75040 {ECO:0000313|EMBL:ESO08331.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP75040, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO08331.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP75040}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the junctophilin family.
CC {ECO:0000256|ARBA:ARBA00008599}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMQM01003193; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096080; ESO08331.1; -; Genomic_DNA.
DR RefSeq; XP_009013261.1; XM_009015013.1.
DR AlphaFoldDB; T1G1Z7; -.
DR STRING; 6412.T1G1Z7; -.
DR EnsemblMetazoa; HelroT75040; HelroP75040; HelroG75040.
DR GeneID; 20215095; -.
DR KEGG; hro:HELRODRAFT_75040; -.
DR CTD; 20215095; -.
DR eggNOG; KOG0231; Eukaryota.
DR HOGENOM; CLU_008078_4_1_1; -.
DR InParanoid; T1G1Z7; -.
DR OMA; QHRENAC; -.
DR OrthoDB; 5393283at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030314; C:junctional membrane complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR InterPro; IPR017191; Junctophilin.
DR InterPro; IPR003409; MORN.
DR PANTHER; PTHR23085; GH28348P; 1.
DR PANTHER; PTHR23085:SF16; GH28348P; 1.
DR Pfam; PF02493; MORN; 7.
DR SMART; SM00698; MORN; 5.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
SQ SEQUENCE 383 AA; 42070 MW; DA913545185EFCD1 CRC64;
MEQPFNGTAL SQNFEELKFE DGGVYYGGTN GGKAHGYGIC TGPGGEGQYS GAWSGGFEVN
GSYSWPNGNA YHGQWLQGKR HGLGMEKRNH WIYQGELTNG LFGKYGVKKH QFTDARYEGT
WSSGVQCGYG VETYADKGTY VGQWQKGARH GYGIRTSSTF KLAATSPQSY ALSRKFSLTS
ARIPPPHIYE KISHTKLLPV NRIGFFLKGK YNDQEPEALK TSDQTKFVDK TLKGNIEYLQ
QNNSGSAVLS DEQSTSKNIN KMSLTANSSN LLCLNSVPEE ACEIYSGEWK NDKRNGFGVC
HRSDGLKYEG EWSDNCKNGH GVTTFSDGSK EEGLYKNNVL TEAMKRLNVL KLGKTKELID
AAASSANKAA QIASQKAQIA ISR
//
