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Database: UniProt
Entry: T1G2V1_HELRO
LinkDB: T1G2V1_HELRO
Original site: T1G2V1_HELRO 
ID   T1G2V1_HELRO            Unreviewed;       550 AA.
AC   T1G2V1;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   25-OCT-2017, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO05570.1, ECO:0000313|EnsemblMetazoa:HelroP77257};
GN   Name=20215399 {ECO:0000313|EnsemblMetazoa:HelroP77257};
GN   ORFNames=HELRODRAFT_77257 {ECO:0000313|EMBL:ESO05570.1};
OS   Helobdella robusta (Californian leech).
OC   Eukaryota; Metazoa; Lophotrochozoa; Annelida; Clitellata; Hirudinea;
OC   Rhynchobdellida; Glossiphoniidae; Helobdella.
OX   NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP77257, ECO:0000313|Proteomes:UP000015101};
RN   [1] {ECO:0000313|EnsemblMetazoa:HelroP77257, ECO:0000313|Proteomes:UP000015101}
RP   NUCLEOTIDE SEQUENCE.
RA   Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Simakov O., Marletaz F.,
RA   Cho S.-J., Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T.,
RA   Lv J., Arendt D., Savage R., Osoegawa K., de Jong P., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ESO05570.1, ECO:0000313|EnsemblMetazoa:HelroP77257, ECO:0000313|Proteomes:UP000015101}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H.,
RA   Aerts A., Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V.,
RA   Lindberg D.R., Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
RN   [3] {ECO:0000313|EnsemblMetazoa:HelroP77257}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AMQM01003822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KB096325; ESO05570.1; -; Genomic_DNA.
DR   RefSeq; XP_009016203.1; XM_009017955.1.
DR   EnsemblMetazoa; HelroT77257; HelroP77257; HelroG77257.
DR   GeneID; 20215399; -.
DR   KEGG; hro:HELRODRAFT_77257; -.
DR   CTD; 20215399; -.
DR   OMA; CPQVARP; -.
DR   OrthoDB; EOG091G0JQU; -.
DR   Proteomes; UP000015101; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013621; Ion_trans_N.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08412; Ion_trans_N; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000015101};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM     72     97       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    103    121       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    241    262       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    315    333       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      418    534       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
SQ   SEQUENCE   550 AA;  63491 MW;  DCA7A42F8A385C7A CRC64;
     MKGSFSFKEL SKSGALSTST SYLKEQITSV FQPSDNKLAM KLFGNKMALK KEKERQEAVG
     KWVIHPCSNF RFYWDFIMLI FLIANLISLP VTITFFHDDL PNTWITFNAV SDTIFLMDLI
     INFRTGYITN TTTNYFTGII ADNFADEIIL EPHHIAVHYL KTWFLLDFLS SIPLDHVIVL
     FTPDAEGISQ IIHAGRALRF FRLVKLLSLL KLLRLSRLVR YVSQWEEVSL FISVAGKFIR
     IFNLISFILL LGHWNGCLQW LVPMLQDFPS NSWPALEELQ NVHWLEQYTW SLFKALSHML
     CIGFGRFPPQ SSTDVWLTMV SMLTGATCYA LFVGHSTTII QSFDTAKRLY REKFKQVEEY
     MMYRKTPKHL RQKITDYYQH RYRGKMFDEK SILSEVNECL REDIINYNCR SLVAAVPFFT
     HADPNFVTDV VTKLEYEVYQ PGDYVIKEST IGTKMYFIQE GIVDIVTKDG DVATSLSDGS
     YFGEICLLTN SRRCASVRCE TYCNLFSLSV ENFNSVLDHY PLMRRTLESV AAERLNKIGS
     SSSSFSSVFV
//
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