ID T1G3W4_HELRO Unreviewed; 270 AA.
AC T1G3W4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN Name=20215762 {ECO:0000313|EnsemblMetazoa:HelroP80006};
GN ORFNames=HELRODRAFT_80006 {ECO:0000313|EMBL:ESO03757.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP80006, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO03757.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP80006}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01004541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096590; ESO03757.1; -; Genomic_DNA.
DR RefSeq; XP_009018314.1; XM_009020066.1.
DR AlphaFoldDB; T1G3W4; -.
DR STRING; 6412.T1G3W4; -.
DR EnsemblMetazoa; HelroT80006; HelroP80006; HelroG80006.
DR GeneID; 20215762; -.
DR KEGG; hro:HELRODRAFT_80006; -.
DR CTD; 20215762; -.
DR eggNOG; KOG0516; Eukaryota.
DR HOGENOM; CLU_005217_5_2_1; -.
DR InParanoid; T1G3W4; -.
DR OMA; KPPKYQV; -.
DR OrthoDB; 2897437at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR SMART; SM00033; CH; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS50021; CH; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 5..111
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 129..234
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 270 AA; 31899 MW; 1FF45D555C65EEEC CRC64;
DERDLVQKKT FTKWVNKHLI KVVQQRHLIS DLFEDLRDGL NLITLLEVLS HRRFPRERGR
MRCHMMQNVQ TVLHYLNRKR IKYVNIRADE IVDGNPKLTL GLIWTFILHY QVGDVVVRGQ
PVTAAATDAS IKEALLLWCQ KMVEGYPGVK VKDFSRSWRD GLALLAILHR HRPDLVDFNR
ARRQPPRANL TSAFEIAEQV YGVTPLLDAE DVDVDDPDER SIITYVSFLY ELFPDSTTGE
RSARENVSHH RRRRHRHLCY YRYFNFYFNN
//
