ID T1GJZ3_MEGSC Unreviewed; 1198 AA.
AC T1GJZ3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
OS Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC Phoridae; Megaseliini; Megaselia.
OX NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA003803-PA, ECO:0000313|Proteomes:UP000015102};
RN [1] {ECO:0000313|Proteomes:UP000015102}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Durham, NC isolate 2 -- Noor lab
RC {ECO:0000313|Proteomes:UP000015102};
RA Hughes D.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MESCA003803-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; CAQQ02131977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02131978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02131979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02131980; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1GJZ3; -.
DR STRING; 36166.T1GJZ3; -.
DR EnsemblMetazoa; MESCA003803-RA; MESCA003803-PA; MESCA003803.
DR HOGENOM; CLU_008532_0_0_1; -.
DR OMA; DHAGQQV; -.
DR Proteomes; UP000015102; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd22405; KH-I_Vigilin_rpt1; 1.
DR CDD; cd22413; KH-I_Vigilin_rpt10; 1.
DR CDD; cd22414; KH-I_Vigilin_rpt11; 1.
DR CDD; cd22416; KH-I_Vigilin_rpt13; 1.
DR CDD; cd22417; KH-I_Vigilin_rpt14; 1.
DR CDD; cd22418; KH-I_Vigilin_rpt15; 1.
DR CDD; cd22406; KH-I_Vigilin_rpt2; 1.
DR CDD; cd22407; KH-I_Vigilin_rpt3; 1.
DR CDD; cd02394; KH-I_Vigilin_rpt6; 1.
DR CDD; cd22410; KH-I_Vigilin_rpt7; 1.
DR CDD; cd22411; KH-I_Vigilin_rpt8; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 13.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10627:SF31; DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A; 1.
DR PANTHER; PTHR10627; SCP160; 1.
DR Pfam; PF00013; KH_1; 13.
DR SMART; SM00322; KH; 14.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 12.
DR PROSITE; PS50084; KH_TYPE_1; 13.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000015102};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 60..136
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 137..205
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 209..277
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 320..385
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 390..457
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 461..530
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 535..604
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 605..658
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 663..732
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 736..805
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 809..896
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 897..963
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 975..1044
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 1048..1117
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1158..1198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 948..975
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1198 AA; 133679 MW; 57F48B670B790ECB CRC64;
MEDSSLNDVQ QQSQENHGGA GQPAFSYDDL FPALPANAAP KASAGPTTVK QNHQMRVGTS
VITQVFHVPC EERKTSSDSE TNFGEGENLR TCQSIMKETG AHIEISSGKD HSLTFLVKGK
PNEVLEARRK ILTDFQTQAS KQISIPKEHH RVILGKKAER LRELEKVTAT KITVPNQTDE
SDIITISGTK EGIEKAEYEI RSMSNEQLKK AVERINVPRK YHPFISGPFN ETVSQLMSET
GAKIHIPPAS VNKDEIMITG EKDAVVTARN KIEVIYKDME KKCATVSVEV ANSPSDTITL
RGPQIALGHA LTVVYQKANS VKSLDLEAPV WIHKYIIGKK GASIKEFEAN NPNVNLDFTA
EDKIKIEGEP DKVDQAAAHL REIVQNYVKN YSFVIIPVNP NHYKHIIGKS GANINRLKDD
LKINVSFDTR DGDNHIRIEG PKEGVLQAQR ELQEKIDKLE NEKSKDVIID RRLHRSIIGP
RGEKIREFKE RYGQVNIAIP SPSENTDIIK IRGPKEDVDK CHKDLLKLVK ELQENSFVVD
VPIFKQFHKY IIGKSGANIK KIRDETQTKI DLPAEGDANN EVIVITGKKE NVLEAKERIQ
YHNSLIGGGG KLISAIMEEC GGVTIKIPSS DSKSDKIIIR GPGEDVLKAK EQLLELASEA
QLASFTAEVR AKQQHHKFLI GKNGASIRKI REATGARIIF PNNNDEDKEV ITIIGKEESV
KLAKEQLETI IADIDKVTDG EISVDPKYHK HFLTKRGEIL QRISDECGGV LISIPPMETN
SDRVTLKGAK ECIEAAKKRI QDIVNDLEAQ VSVEVIIPQA HHGNIMGQRG SRIQQITSKY
DVQIKIPDRN ATELVPIVNG ESGEEPTTAR QCDIITITGT IEKCNAAKQV LLDLIEITEE
VHVPFEMHRS IIGQGGRSVK ELINRYEVRI ELSPPDSKLD IIKVTGIKTN VSEAKEALLK
KVEEFEAEKK DRELRSFEVK VDIDPDYHSK IIGRRGAVVN KLRADFDVNI SFPKAGDEDN
RTVTITGYEK NANECKEEIL KMISDYNDYI KEVVNIDARV HPRLIGNRGR NIKKIMEDYK
VDIKFPKATD EDKNAVTIIG HEENVENVKD HLLNLEEEYL QDVIDVAPSH RNQSSDLSAA
FEQAFNQTGF VVKGAPWERQ KGSAPNTQSQ EDFPDFGGKT NSNSETAPIS SAWGGSRH
//
