ID   T1GPQ3_MEGSC            Unreviewed;       279 AA.
AC   T1GPQ3;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Acid phosphatase {ECO:0008006|Google:ProtNLM};
OS   Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC   Phoridae; Megaseliini; Megaselia.
OX   NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA005592-PA, ECO:0000313|Proteomes:UP000015102};
RN   [1] {ECO:0000313|Proteomes:UP000015102}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Durham, NC isolate 2 -- Noor lab
RC   {ECO:0000313|Proteomes:UP000015102};
RA   Hughes D.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:MESCA005592-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC         Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000032};
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC       {ECO:0000256|ARBA:ARBA00005375}.
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DR   EMBL; CAQQ02024531; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02024532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02024533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02024534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02024535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1GPQ3; -.
DR   STRING; 36166.T1GPQ3; -.
DR   EnsemblMetazoa; MESCA005592-RA; MESCA005592-PA; MESCA005592.
DR   HOGENOM; CLU_998497_0_0_1; -.
DR   OMA; NETFYPN; -.
DR   Proteomes; UP000015102; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 2.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR11567:SF205; GH28721P-RELATED; 1.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 2.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015102};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   279 AA;  31987 MW;  671D9667AC8494EC CRC64;
     MASSQSVRNQ RIAMSFGFVI LVIVLLYCLI GTVYSGAISR SRPARFQQSS KKDTLQLLHV
     VFRHGARTPA DTYPLDPYFN ETFYPNGWGQ VFRHGARTPA DTYPLDPYFN ETFYPNGWGQ
     VTNDGKDKLY KMGIWLHDRY GKFLGEYMPD SVYAQATGVS RTHVSLQTVL AGLYRPRNTA
     LDWNRNLNWL PIPVFSQPLE EDSLLLVRTP CPRYYEARDD VYKLPEIASL HEKYKDMMKE
     LSDHTGKHIE NAEDVADVYT TLLAEKEFAC PFLGPHVSK
//