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Database: UniProt
Entry: T1GR78_MEGSC
LinkDB: T1GR78_MEGSC
Original site: T1GR78_MEGSC 
ID   T1GR78_MEGSC            Unreviewed;       186 AA.
AC   T1GR78;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   07-JUN-2017, entry version 13.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Platypezoidea; Phoridae; Megaseliini; Megaselia.
OX   NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA006154-PA, ECO:0000313|Proteomes:UP000015102};
RN   [1] {ECO:0000313|EnsemblMetazoa:MESCA006154-PA, ECO:0000313|Proteomes:UP000015102}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Durham, NC isolate 2 -- Noor lab
RC   {ECO:0000313|EnsemblMetazoa:MESCA006154-PA};
RA   Hughes D.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:MESCA006154-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; CAQQ02027319; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02027320; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02027321; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EnsemblMetazoa; MESCA006154-RA; MESCA006154-PA; MESCA006154.
DR   Proteomes; UP000015102; Unassembled WGS sequence.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000015102};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015102};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   186 AA;  21282 MW;  23808120EFF60082 CRC64;
     MESDQLKTRV KKICEGFRAT LYPCPESPSD RREMAMGVMT RIEDLNTVLG QTQDHRHRVL
     VAAAKNLKNW FVKVRKIKAI YHTLNLFNLD VTKKCLIAEC WVPVLDIETI RVALSRGTER
     SGSSVPPILN RIENFENPPT YNRTNKFTKA FQALIDAYGV ASYREMNPAP YTIITFPFLF
     AVCLVI
//
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