ID   T1GWH1_MEGSC            Unreviewed;       414 AA.
AC   T1GWH1;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Receptor ligand binding region domain-containing protein {ECO:0000259|Pfam:PF01094};
OS   Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC   Phoridae; Megaseliini; Megaselia.
OX   NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA008148-PA, ECO:0000313|Proteomes:UP000015102};
RN   [1] {ECO:0000313|Proteomes:UP000015102}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Durham, NC isolate 2 -- Noor lab
RC   {ECO:0000313|Proteomes:UP000015102};
RA   Hughes D.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:MESCA008148-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; CAQQ02130480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02130481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02130482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02130483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CAQQ02130484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1GWH1; -.
DR   STRING; 36166.T1GWH1; -.
DR   EnsemblMetazoa; MESCA008148-RA; MESCA008148-PA; MESCA008148.
DR   HOGENOM; CLU_664943_0_0_1; -.
DR   OMA; NGEICRT; -.
DR   Proteomes; UP000015102; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007154; P:cell communication; IEA:UniProt.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR44755:SF11; ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1; 1.
DR   PANTHER; PTHR44755; NATRIURETIC PEPTIDE RECEPTOR 3-RELATED; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015102};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..414
FT                   /note="Receptor ligand binding region domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004588563"
FT   TRANSMEM        334..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..240
FT                   /note="Receptor ligand binding region"
FT                   /evidence="ECO:0000259|Pfam:PF01094"
SQ   SEQUENCE   414 AA;  46814 MW;  EE8D50094D67B61B CRC64;
     KLFLLFKVIL GGLPLAVEAV NKNPTLLKNR KLSFWPVDIG RKNGTFGYSV QPIRSMTEMR
     DKKVVAFIGP GDGCTSEALL AAAWNMPMIS FKCSDSVVSN KEIFHTFART LAPASKVSKS
     VISLLLNFHW KKFAIIAGTR PYWGPEVAKA IRDLAETEKL TITHFREVSD HIPTDSTINR
     MQEIVDETYE TTRIYVFIGE QIGMVDFVRC LQNRNLLTSG EYMVISVDDE IYDPAVRDNT
     MQTRFDVHID SNGDAEGNYT VICMLDEPGY KNNIGKMSMQ PVGYFVFTTS SLPEFRYSKL
     DRQIPWLRGS PPRAEPVCGF KGELCPPKPV DWKYITLSVC IALVFMIAGA FLIKHYRYEQ
     TLAGLLWKVD IKDVTFIIEN IEMNGKAKNC FQPCRQSFLN GADTTKRAYT SIGR
//