ID   T1HA78_RHOPR            Unreviewed;       230 AA.
AC   T1HA78;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=Neurotransmitter-gated ion-channel transmembrane domain-containing protein {ECO:0000259|Pfam:PF02932};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC000933-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|Proteomes:UP000015103}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC000933-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
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DR   EMBL; ACPB03024495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1HA78; -.
DR   STRING; 13249.T1HA78; -.
DR   EnsemblMetazoa; RPRC000933-RA; RPRC000933-PA; RPRC000933.
DR   VEuPathDB; VectorBase:RPRC000933; -.
DR   eggNOG; KOG3644; Eukaryota.
DR   HOGENOM; CLU_1206096_0_0_1; -.
DR   InParanoid; T1HA78; -.
DR   OrthoDB; 2874625at2759; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProt.
DR   GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:UniProt.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   CDD; cd19049; LGIC_TM_anion; 1.
DR   Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR   InterPro; IPR006028; GABAA/Glycine_rcpt.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR038050; Neuro_actylchol_rec.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   PANTHER; PTHR18945:SF843; IP12572P-RELATED; 1.
DR   PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR   Pfam; PF02932; Neur_chan_memb; 2.
DR   PRINTS; PR00253; GABAARECEPTR.
DR   SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103}.
FT   DOMAIN          50..89
FT                   /note="Neurotransmitter-gated ion-channel transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF02932"
FT   DOMAIN          112..152
FT                   /note="Neurotransmitter-gated ion-channel transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF02932"
SQ   SEQUENCE   230 AA;  25523 MW;  7F25EAB3EB7C1B5C CRC64;
     MGKGLRMPQF EIVQIEASNC QESFQIGNYS CLVAEFYLSR SVGFHLVQSY LPTILIVVIS
     WVSFWMDVDS VPGRTTLGVT TLLAVSSQSS GMHIIGLFVE LGYRRSNSKR GIQSGLPQVS
     YVKAIDVWMG TCTAFVFCAL LEFTIVNYMW RKVVEQPAPP PPPVPQVPDL NGDLKQDQPS
     LVPIASHLAK SEGLTLISQG TETTLAFQTT VEISSLRIQH LGVFYNFRRC
//