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Database: UniProt
Entry: T1HAZ2_RHOPR
LinkDB: T1HAZ2_RHOPR
Original site: T1HAZ2_RHOPR 
ID   T1HAZ2_RHOPR            Unreviewed;       502 AA.
AC   T1HAZ2;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   05-JUL-2017, entry version 24.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Paraneoptera; Hemiptera; Heteroptera;
OC   Panheteroptera; Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC001198-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|EnsemblMetazoa:RPRC001198-PA}
RP   NUCLEOTIDE SEQUENCE.
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC001198-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; ACPB02029660; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EnsemblMetazoa; RPRC001198-RA; RPRC001198-PA; RPRC001198.
DR   VectorBase; RPRC001198-RA; RPRC001198-PA; RPRC001198.
DR   OMA; XEHSGST; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000015103};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    382    407       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       51     85       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   502 AA;  58059 MW;  4A1DFF39CA360BB2 CRC64;
     MSAFQRKFVS EVRRCEEVER KLRYIAAEVK KDDVCIPELQ EIPEAPNPRE LIDLEAQVER
     TENEIQELSH NATNLRSNFV ELTELRNVLE KTDAFFQERK VHQILSANVT CGSQIPLTNV
     ISYFRRWMKK IELKKRKLGM CRKSRIRRIN PLNAANGLRR LVFGQCLLVL APLVHRFCFL
     QSVCFQQQEG ESVSRALIGD EPSSRTQLGF VAGVVPRERV FSFERMLWRI SRGNVFLRRA
     DIEEPLLDPT TGKLLVKTVF VAFYQGEQLK TRVKKVCSGF HATLYPCPCT LAERNTMVTE
     VKTRLEDLNM VLNQTDDHRQ RVLVTVAREI PKWTVMIRKM KAIYHTMNMF NMDVTKKCLI
     GECWVPTRDL GTVNRALADG GIWNIFFAGR YIVLMMGLFS MYTGFIYNDI FSRSLNIFGS
     SWKINYNTST VFTNEMLQLD PATDDYNKKP YPFGIDPVWQ TLSQSCLYSS GISTPGIVPN
     SFVPLHGCHD VYEVRHVRRR KP
//
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