ID T1HX06_RHOPR Unreviewed; 748 AA.
AC T1HX06;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Guanine-nucleotide releasing factor {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC008576-PA, ECO:0000313|Proteomes:UP000015103};
RN [1] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:RPRC008576-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
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DR EMBL; ACPB03001559; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1HX06; -.
DR STRING; 13249.T1HX06; -.
DR EnsemblMetazoa; RPRC008576-RA; RPRC008576-PA; RPRC008576.
DR VEuPathDB; VectorBase:RPRC008576; -.
DR eggNOG; KOG3629; Eukaryota.
DR HOGENOM; CLU_010252_0_0_1; -.
DR InParanoid; T1HX06; -.
DR OMA; KCNPYYA; -.
DR OrthoDB; 68574at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00153; RA_RalGDS_like; 1.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF312; RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE, ISOFORM E; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00314; RA; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015103}.
SQ SEQUENCE 748 AA; 85448 MW; 8D9D2166BE6B464C CRC64;
QPTWKVWGEE RLDGAIYTIY LKKVRYHRPT FTVTTDDSNE SISHLEWETV RVRLLKAGTL
QRLVEALATD EGELESTYVN VFLATYRTFT TPHQVLTLLL DSYHSQPLKT DQRIYETELN
IIKIFYKYRL LIMLKEHEKW TLCGALHVWL ESYPEDWNQP PLHPMIHQLL LFTQQYLPNS
ELHIKLKHRL HSLQSVNKNN GKSFSSFNNN LFSKAQKRLL TIYFADVYSA YNGTLCLHTS
SAQPPCHFPD IPHQHFAEQL TRIDMELFKK VVVHQCLGGV WSRREKRRAE EAPTVLATVT
QFNAVSLRVI STVLIHASTP RSTIIANWID VAQELRVLKN FSSLKAIISG LQSNPVYRLS
KTWAALPKDK VELFEELARI FSEENNQWAQ RELLMREGTA RFADTVGQND RQLQKVIQRQ
LNNSGTISYG TIPYLGTFLT DLTMIDAAIP DMLPDGLINF DKRRKEFEVL AQIKLLQGAA
NAYAITEDLS FERWFDSVLT LDDKEAYQLS CQIEPPPMNT PINLRISNNL WVIYLGTSAL
EDPSKQGHRK NDSVASTSSS SSSQFYCDID HTSTSIDTKV KRNFSENNFF IVPYTSTNKF
SLKTKNVRAR EIFTFLGNLP GKGVSQTSSS SNGSIDTTPL SPSLNISQGA TDFYIIKVTY
QTDNVETEGI VLYKSIMLSN NERTPQVIRN AMMKLGLEGN PDSYTLAQIL PHKEMVLPPN
ANVYYAVNTE YNLNFILRPK DQPSPSGY
//
