ID   T1ISE0_STRMM            Unreviewed;       997 AA.
AC   T1ISE0;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Vacuolar protein sorting-associated protein 11 homolog {ECO:0000256|PIRNR:PIRNR007860};
OS   Strigamia maritima (European centipede) (Geophilus maritimus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX   NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR004009-PA, ECO:0000313|Proteomes:UP000014500};
RN   [1] {ECO:0000313|Proteomes:UP000014500}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA   Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA   Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA   Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA   Muzny D.M., Gibbs R.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SMAR004009-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Late endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004492}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004492}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004492}.
CC   -!- SIMILARITY: Belongs to the VPS11 family.
CC       {ECO:0000256|ARBA:ARBA00007070, ECO:0000256|PIRNR:PIRNR007860}.
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DR   EMBL; JH431430; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1ISE0; -.
DR   STRING; 126957.T1ISE0; -.
DR   EnsemblMetazoa; SMAR004009-RA; SMAR004009-PA; SMAR004009.
DR   eggNOG; KOG2114; Eukaryota.
DR   HOGENOM; CLU_001287_0_1_1; -.
DR   OMA; ENECPAC; -.
DR   OrthoDB; 5491867at2759; -.
DR   PhylomeDB; T1ISE0; -.
DR   Proteomes; UP000014500; Unassembled WGS sequence.
DR   GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0099023; C:vesicle tethering complex; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd16688; RING-H2_Vps11; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR016528; VPS11.
DR   InterPro; IPR024763; VPS11_C.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR23323:SF24; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG; 1.
DR   Pfam; PF00637; Clathrin; 1.
DR   Pfam; PF12451; VPS11_C; 1.
DR   PIRSF; PIRSF007860; VPS11; 2.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50236; CHCR; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR007860};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          813..851
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          939..997
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        946..963
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   997 AA;  114556 MW;  E927AA5F2F068A1F CRC64;
     MAFLQVWRRF KFFDKEVVKD GNGQIFDKLK DISITACTSG RGLIILGDVE GIVYYITRQL
     ELISFKAYEL TVNNLQQLRQ NNILVSTGED VPGNNPVIKI WNFDKCDKNG LPLCTRSVTA
     LPGNKETPAT ALAVHENMNF MALGYDNGSV LLFRGDISRD RGSKHKILHE GPNSVTNLAF
     RNTNKIIHLF VSTTEEIYCY NIHTKDKDFK YLLEDKGCLS RCSTMSDATL EYQFVVARTD
     AVYFYQPDGR GPCFAFDGKK IILHWFRGYL VAVGKDGGAP SGSGGQSLAM NIVTVYDIQN
     KFIAYSAPLP EVIDVVSEWG SLYVLGGDKK LYHLQEKDTQ SKLDMLFKKS LYALAIELAK
     SQQYDEDGVV DIFRQYGDHL YSKGDHDGAI EQYIKTIGKL EASYVIRKFL DAQRIHNLTA
     YLQALHKQGL ATEDHTTLLL NCYTKLKDTD KLNEFIKTKD GSVDFNVEIA IRVCRQACYY
     RHALLLSEKE GQHDWYLKIQ IEDLQDYQTA LSYISKLDFI EAESNMKKYG KMLMTIIPNE
     TTQFLKQLCT DFRPSNKPLV DVSMLDGSKP MKIERAEAKD FIHIFVNNSK HLVSFLEHTI
     KIPLYPAQHS SLVYNTLIEL YLQEYNQETE DNLKIEHEIK ILNLLQSPDS GYDLDQVLVL
     CQMNNFKPGI LYLYEKAKLF QQILRYYMDR DDFNNVINTC KHFGSQDSKL WIQALWYFSK
     TDDRQKNYLI EILQHIERER LLSPLMVVNT LASSSLTTLA VIKDYIIKQL QKENQQIAED
     EAMIKQYRDD TGKMRKEIED IKHNPREFKV AKCSACNQQL ELPSVHFLCH HSYHMHCFES
     YAENENECPA CMPENRKVLE IIKAQEENRE LHEIFHHQLE VAEDGFSVVS EYFGRGIFNR
     VTLVTEALVH KRPPSLSRIP IVEPARSIKL PPVERLDLPR NSKIRGPMSL PSSSNQLLTR
     TYPKTKNPFE AGAPNPFESA PNPFEDPYDD SLNPFES
//