ID T1ISS6_STRMM Unreviewed; 757 AA.
AC T1ISS6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR004160-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR004160-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; JH431446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1ISS6; -.
DR STRING; 126957.T1ISS6; -.
DR EnsemblMetazoa; SMAR004160-RA; SMAR004160-PA; SMAR004160.
DR eggNOG; KOG0489; Eukaryota.
DR HOGENOM; CLU_368166_0_0_1; -.
DR OMA; MESRCET; -.
DR OrthoDB; 728401at2759; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001827; Homeobox_Antennapedia_CS.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR45664:SF2; HOMEOTIC PROTEIN PROBOSCIPEDIA; 1.
DR PANTHER; PTHR45664; PROTEIN ZERKNUELLT 1-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00032; ANTENNAPEDIA; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000014500}.
FT DOMAIN 109..169
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 111..170
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 30..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 82243 MW; E2AC19DA321DC459 CRC64;
MESRCETGFI NSQPSMAEFM TSLPHINETF HRGSSITGTG MPPPPMCGPL DEQGQLHTVA
GTTPTGPPPP VTKCAAGAAA GMGVPVPEYP WMKEKKTTRK THQDTQENGM PRRLRTAYTN
TQLLELEKEF HFNKYLCRPR RIEIAASLDL TERQVKVWFQ NRRMKHKRQT MGKGSDDGVG
PTTGGSGGKG VGPGDADDGC SLSGHESSNL KGCRDASVKS DGADTPSSPS SSCDSQSKAE
VSELPTLASP PQHKADPGID IVTGHSSPDK YINGLSPLNH VPPPLDVSVE QKLVCHPPNG
LCSPVGNSPP TGPLSNGHNT VFTLPSPASS VGSPGQISRV RIKVTPIQGA CSTGPPSKRR
KSEFTEPLSS ASSHGSPLEN GMPSYYTATP TTYQPSTRHS PGTRSYVYPQ CSQNMQHEYR
QTPHQYPRSS TAGIMNYPSS SPRADHYYPD MHCNSSRGDQ GSYTGPLNQH GQQQIRSSPP
DNYRTSPGIS RQTSSTPVPV SSVPPGQTNT RLNGVYNAPN RLPPISQQSQ QARVYAFGNN
SNMSNTAQPN TCTPHYNEGY VQTYTTNGYE TGYNYGDDTR LMNGEQEHHH QQQQQQQQQQ
QYVQSNNEHN SIDFAGYAFT SDPIGYQTGP RGYTQTTPDM TPPADQLQTS IMQDQYYSDG
NTGSQFATGN VSDYATAPKQ NLAPVVNFYE GQGSVGDTPN IPAITPSPEE QFSNGSSEPD
VNFTFNFFDQ SSQNSHSDFN FLTNLANDFS PEYYQLS
//
