ID T1ITU1_STRMM Unreviewed; 773 AA.
AC T1ITU1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=MAM domain-containing protein {ECO:0000259|PROSITE:PS50060};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR004549-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR004549-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; JH431501; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1ITU1; -.
DR STRING; 126957.T1ITU1; -.
DR EnsemblMetazoa; SMAR004549-RA; SMAR004549-PA; SMAR004549.
DR eggNOG; KOG1215; Eukaryota.
DR HOGENOM; CLU_361829_0_0_1; -.
DR OrthoDB; 3088253at2759; -.
DR PhylomeDB; T1ITU1; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 1.
DR CDD; cd06263; MAM; 1.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR23282; APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR; 1.
DR PANTHER; PTHR23282:SF142; MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR Pfam; PF00629; MAM; 3.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00192; LDLa; 2.
DR SMART; SM00137; MAM; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 2.
DR PROSITE; PS50060; MAM_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..773
FT /note="MAM domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004579546"
FT TRANSMEM 652..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..175
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 182..316
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 336..455
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DISULFID 519..531
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 526..544
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 538..553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 773 AA; 86935 MW; 94F474384C41CD8E CRC64;
MKALLLVAIL NFPLVLSQET GIDCKFNNYS LCGWQQDQTD NFDWLPYCKD DDIQNCLVYI
ESTSPHRANE QSRLVSPNIV PNSQTQCFSF SYHMFGVRVN SLNIYIKKSD GQSQLIWHRK
HSRANIWHRG YRTIESSTEY KIIIEAVAGH PVNSIKSDGI IAVQSTELIE GICAPLLQQA
DYYCDFEEDF CMWYSGSNWM RNTSLNIALP HKPAKDYTTG TDNGYFAYIS TDEDKTSIST
NFSSPKLTTT SEERCVQFYY YMERGTRAQI DVYIVYEDRE FQLLCSQMGV EDNYWAFAEV
AVTDHKKQNH WVKIIITRGE TVVEAAYNMP EFDISHTDAG YFLFVDLANA QPNQKATLSS
KPINPCPVCL TFEYFTQGEN FDGKLEILIK NWSGERIQAT ISHVTNDWTK HTQSISQDCG
FKPYEIYIRA TAGNGKGFIA IDNLSTKVTS DDCKTTPPID TKTSSTAHHK VTTRPTTPSL
TATTTSFAAT TTTLAATTTT LPDTTLSLKY TPILTQNKCD NGTLDCGDGS CILAIYLCDG
VKDCHNNADE LTCALTCQDR KSNSYCEGFN WPQCLSNNHL CDGIADCINN ADENKHLCGG
CPNTYCVTGR CIPDGSKMPH CICNNDEHHG RRCEYLKPIK ETPSAASPPN DYTIWIMVPM
MTLLVVVIAI LLINLYCYRK YKWYHAAGLL GQKNNRSLYR RNSMNTTEMT PTNVNVEEVA
DDVGLTEAPQ RRAVREDAIS MIQTPLTNYK LHSLYIGKVV LDDDGNIVAV SNA
//
