ID T1J1M8_STRMM Unreviewed; 606 AA.
AC T1J1M8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Dystrophin {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR007450-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR007450-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004278}.
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DR EMBL; JH431789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1J1M8; -.
DR STRING; 126957.T1J1M8; -.
DR EnsemblMetazoa; SMAR007450-RA; SMAR007450-PA; SMAR007450.
DR eggNOG; KOG4286; Eukaryota.
DR HOGENOM; CLU_001187_1_2_1; -.
DR OMA; QSETTHW; -.
DR OrthoDB; 4105031at2759; -.
DR PhylomeDB; T1J1M8; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0016010; C:dystrophin-associated glycoprotein complex; IEA:UniProt.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007154; P:cell communication; IEA:UniProt.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IEA:UniProt.
DR GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:UniProt.
DR GO; GO:0023052; P:signaling; IEA:UniProt.
DR CDD; cd00201; WW; 1.
DR CDD; cd02334; ZZ_dystrophin; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 6.10.140.70; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR015154; EF-hand_dom_typ2.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268:SF18; DYSTROTELIN; 1.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR Pfam; PF09068; EF-hand_2; 1.
DR Pfam; PF09069; EF-hand_3; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..33
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 255..311
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT COILED 397..427
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 606 AA; 69504 MW; DEF18CD029D0D712 CRC64;
KILDGWEKKR TENDVPYYLC HVTQCSQWEH PLLNTVMEEL SDYKIVKYST YRLALKLRAL
QNVFKLHLVS TEILVKIYNQ VAVKPVISES TMSCTELELF LYDVFNIARV EQNSLTDPRV
SAELCLNFLI NLFDSTRSGV INVFSVFVGL LIFSMGKLHE KYKFLFRILA NHNNCMTKNS
LTFLLNILAE IPERLNEKIT FGKTFVAAAV ESCFSNKSSP LGITEEMFLS WLLQEPQTVV
WISTFFRLVT AESVLHAVKC CVCKMYPITG LRYRCLYCFS YDLCQHCFLT GQISKKHKLK
HPIQEYCTTA TSKEDRKVMM KRLGNKLKMK KNKQSFLPIR PTQTIPEVDV FENQHATIPD
IPATPIVTHK TVTPGQEFLS CTILNGMPMK TFLASQQNEL ESVIIHLEQQ QKLLRNELDQ
LDQLDQQDLS LSSSSDDAKS TASCHSTVSR QEVLLDHEKQ LELQLRRLKR ILKSFNKMCK
NADQVNSVEN DDEMPFAATS TPNYVSVEVH NQPMDREMPS PIVTNDFLRE NRNISNGLQT
DSTRELNQIQ DELDSIMKHL ELTFPDNKQT KDGAQSESDD LLKAAIDVSD ILADLVDKVR
INRTTQ
//
