ID T1JD49_STRMM Unreviewed; 1830 AA.
AC T1JD49;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Down syndrome cell adhesion molecule {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR011727-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR011727-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
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DR EMBL; JH432094; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EnsemblMetazoa; SMAR011727-RA; SMAR011727-PA; SMAR011727.
DR OrthoDB; 2405257at2759; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR CDD; cd20958; IgI_5_Dscam; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 16.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170:SF39; FI24025P1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 6.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 10.
DR SMART; SM00408; IGc2; 10.
DR SMART; SM00406; IGv; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 10.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 10.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1578..1601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..89
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 95..190
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 204..295
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 298..382
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 388..481
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 486..572
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 577..664
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 673..767
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 772..864
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 871..966
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 971..1072
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1077..1174
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1178..1272
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1272..1356
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1371..1464
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1468..1562
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1676..1696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1710..1767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1785..1806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1830 AA; 201503 MW; 3AF3ACAA9F43759A CRC64;
EPPNNVDFSN TTGVTIECLA TGDPLPHITW ESSTGTSIGS LDGVREVLPN GDLVFPPFKA
EEFRQDAHAA VYRCAATNAA GTVLSRDVHV RAVVPQPYDI QVYDVYAIVK TTAVLKCHVP
SFLEEHVRVT MWLRDEVLII EPTSIMDGKY AVLPSGELHV RDVEMEDSGS SYRCHVKHSL
TGETHFSSAS GRLYVREPQG SVPPKITDIM TAVHVTEGET VILPCVAQGH SAPKAEWFAK
LNKRQLFPLH IGERVQQTSG ALIIHRAQTS DSGTYVCDVS NEAGNDRGET TLTVTASLTV
SILPEKQVVD IGKSATFRCV VTGFPVVYVS WYKDGRKLQS DAEKTLSDDT ITIASVHVTD
KGMYQCLVSN NQESAQGAGQ LILGDAAPEL VGVFDDNTLE SGTDVSLACV ATGSPAPVIT
WFVDDVSLQT SERIRVVGRA DTDGSIVSVL NVTETRWEDG GTYRCLANNK AGTVEHIARL
NIYGRPAIRP LDKVTAVAGE DVRLNCFYYG YPVTSINWEK DGRALPFNLR QIAFPNGTVV
IRKVQRATDS GKYTCTVVND KGQSAQEHVE MAVMVPPKII PFAFLDDQFY MGMRAHITCA
VSQGDLPISF RWLKDGQELP SALGILTRNY DEHANSLHIE SVTSKHTGNY TCIAANMAAS
INYTAQLLVH VPPRWTLEPR DSSMLLGHSL QLDCQANGFP EPKVTWMKTQ GATVGEFVEP
VEMSPDLSIL SNGSLLFIRA REYHAGHYFC KASNGIGDGL STAVHVTVQV PPRFDVKFVN
QSLKRGEGFR LECPPNGDKP MSFMWKKDGV LLDPLADTRY KIESPADRGV SDLTVEEATR
IDTGIYNCKA ENEFGTDDTN LQITVFEPPD APGDIRIQNI GSRNVHVTWS HPFNGHTRII
KYVVEYNQGP EEWEDGLVEL AVSGWDTNVT LHGLRPATHY QLRMFAENEL GLSSPGDFVT
FLTKEEAPAG APVDVEADAV DANTVVVRWR PPERHVWHGK LRGYTITYYK KLDSTDAPNF
RTVQVEDGSE GNHSAFITDL EKFTKYSLTI SAFNDQGQGP KSEEILVMTS EDVPSEPPTD
VQCLAYTSQS IYITWQAPLS TSFNGILRGY KVFFAKADDT TAEDGSLEFK STTVVRTTLH
GLEKYTNYSL RVAAFTKVGD GAASDFVYCR TMDDVPDVPA DVKAIPASKE SVLVAWKPPL
HSNGVVTKYY VYAKHENDPE EDAMKHTAPP SALYHEISGL KTDQSYEFWV TAATMIGESS
RSKMVSEAPQ GPMVPARIAA FDSVVTTLWK KYIKLPCKAV GNPATERMWT LTPVQSTRAH
TVKESDRLRI LPDGNLMVKN VQWNDSGNYT CQVKNGFGYD QIVYVVNILA PPSAPIINVL
ETTPTSIVLE WKLDTDGGTN VQGYTLNYKR ESGHWEQRDL APDSDSYTLS GLKCGSHYQM
YMTAFNKINT GVASEVIVAA TNGTVADVPA KEDLIDEDVD YVTLDLHVWH SDSCPVSTFK
VEYKQKNSLN WHLLTDELKA EQEKYVIRNL TPGTAYLLRV TALNGAGPSV ATYDFITLSR
QGVHEDPRGI LFYLDLRIII PLAALVIVVI LVLSVTCICA NRRGNAARKM KGMDSQNGPH
RPCLRTDSTL SSFAYLQRHR SSCDGSILRS DTQEKSIPYS TYNLPNLRSS AEFKTFGQRN
SVSDPPPLPP PQNDFDEADA QALQHFSRPP VTNLQSFPSP NGKMQRTGYP VAIPTAPTPP
PQIDANSADQ TGSPGLKKVP EVPPKPNMVT METRFSSSPD KVRVRVLPGA PNNGTSDGFG
SLDKSTLRSP YITNIDTTPA TIPPRYDWRQ
//
