ID T1JDQ5_STRMM Unreviewed; 1146 AA.
AC T1JDQ5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Signal peptide, CUB and EGF-like domain-containing protein 1 {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR011939-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR011939-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; JH432108; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1JDQ5; -.
DR STRING; 126957.T1JDQ5; -.
DR EnsemblMetazoa; SMAR011939-RA; SMAR011939-PA; SMAR011939.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_013079_0_0_1; -.
DR OMA; TCALSCP; -.
DR OrthoDB; 5387502at2759; -.
DR PhylomeDB; T1JDQ5; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR24046:SF5; EPHRIN_REC_LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24046; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF07699; Ephrin_rec_like; 3.
DR Pfam; PF14670; FXa_inhibition; 5.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 9.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM01411; Ephrin_rec_like; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 6.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01186; EGF_2; 7.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1146
FT /note="Signal peptide, CUB and EGF-like domain-containing
FT protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004579550"
FT DOMAIN 210..250
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 292..332
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 451..491
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 492..530
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 531..571
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 944..1055
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 496..506
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1146 AA; 128282 MW; 09573088E04104A0 CRC64;
MHSDTLNFIT LLAPVFFRLF RCDTVDIDLQ RGVVRGYNPF VSFVSSPVRG RGEQCSRQAV
IRLDLSGNFK IAIISLDYDE RPRQWTLDIA ESNTADGHGG NVQYPASEFS VHNRQVRLYS
NGRPGYRSAT IDGGYLLKVI DGVVKQGSRL SIEISPGKVS WAVGGRREDV ESSFVFQTSV
VFAAFNRVVG GSWRNGTGIC RATVNLRRTP PDECLLGTHQ CDVHATCKNT RRAYRCRCKP
GYQGDGKKCQ DRNECSVRNG GCVHKCHNNP GNFTCSCHDG FQLDKDGRNC IDIDECSKRK
GGCVHQCLNT LGSYECRCND GFSLAADGHS CNMGSWCKEQ GCDHSCEVTR SSFICTCRPG
FMLAPDGRNC IQSCSHGNGG CQHRCTHTSD GPICTCHYKY ILGLDKKSCS PSCAINNGGC
DRKCSTTPQG MVKCNCPNGF LLHKDGRSCL DIDECAVKNG GCSHTCLNSH GSFECICPEG
YKLLPNEKTC SEFDECSISG TCDHTCVNTP GSYECVCNSG YEQFGQTHCG DKNECAQNNG
GCHHLCVNTE GSFKCACRQG YFLHPNKKDC IEMDTCKDDE AANPIQVQCR RNKMKETCSL
VCASGLHFSG NRNESYRFEC GSRSTNVCMG NTCSLEFPRR IKFTIISNGC HLLQRITGHQ
MSSRCISVGI ISYVKMFCEP RWKPRWSRDL TEDHTSIIHV DMDVQLGQKF KTSSCNNLCR
EKYTRQFRYV MAFIQRQFQE ELFYVTSPRE KEFLLMTSRT NDTVCPDGQI YLHGKCVFCS
AGNFFDLDKN QCIQCPSGTY QDSSNQFGCH VCPQENMYAS PGSSSLSTCG SECLPGYYSA
DGFQPCTLCP LGKYQPQTGR MFCHVCGKGI NSLSMGSTSF HQCQVPEFCT LGSFYNTSIG
QCQLCPIGFY QPNKGRDFCF ACPGETATDY EGSSDLTQCK SRQCGGSIGK LLGIFESPNY
PGNYPNNIQC TWTIRAQKGR RILVVVPQLF LADDQCGDSL VMRKSKSPYS ITTYDTCKTQ
QRPIAFTARS RKLWIHFKSD GKNNDQGFRI PYALFNEEYQ PLIESIVRDS QLYAMINHQE
ILKDRKLLTA LMDVIAHPIN YYKYANISWA WFPDSFVRFI MSKVKFKEKL MFAHHYFDNF
GEILTN
//
