ID T1JY23_TETUR Unreviewed; 1215 AA.
AC T1JY23;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Nephrin {ECO:0008006|Google:ProtNLM};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur02g14070.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur02g14070.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAEY01000838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAEY01000839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1JY23; -.
DR STRING; 32264.T1JY23; -.
DR EnsemblMetazoa; tetur02g14070.1; tetur02g14070.1; tetur02g14070.
DR eggNOG; KOG3515; Eukaryota.
DR HOGENOM; CLU_003881_1_1_1; -.
DR OMA; CEVSNIM; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45889:SF8; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 8.
DR SMART; SM00408; IGc2; 7.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 8.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 8.
DR PROSITE; PS00290; IG_MHC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1031..1055
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..160
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 170..260
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 265..360
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 368..457
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 464..560
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 565..653
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 658..773
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 777..876
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 883..1008
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 923..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1062..1115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1086..1100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1215 AA; 132519 MW; A5A9BD322BD5C38E CRC64;
MDGNPSEGVH NLKIERASID DDGEYQCQVG PATNNKAIRA NSRLTVLLKP KKIEINGHTN
GSAVEIREGE KVTLTCLVYG GKPAAKIKWF RKDIELKTDN LPNQSVLTVT SSLNEGSSSD
QITATKSQLL LNLHSEDNGV TYSCSASHPA LSNPLRSTVS MSVLYPPGPP EILGYSTGKA
VRSGDTLKLR CRSRGGNPLA QLVWYKDDEQ VDFSFDSYAG RESVNEYIFT VKPEHNNAKL
TCESKTPINP TPMTTSVTLS VQFAPSKVTI VGPDEAKAGD NVTMICKTDA SNPPSELSWS
IDGRTIRTEN IYKSHSKGGY ITTTNITLPI LSTERSMKTF SCFAVNQALD KTVPASHALS
ILYAPFNPSI VGYDESQSLH SGTVKRFTCE SQGGNPLADL KWFKGKEEIT SGWTVTSTVN
GVSSELTLVV TDSDNGAIYR CEASNAASKE PLEASVKLKV YFAPSKVKIK SRPARPKAGN
KVDLICETES SNPASEVVWW RNGQLLPGHV NSTIDSSFGG KSTKNVLKMN VTSSDDGSIF
TCQAINKLLD QSVHDALTLN VLFKPEFISS EPLASFELVE GSEASINLTA RGNPSNIKYK
WHRINGNGEL DATRFYTDGP ILNITSVLRQ DSGSYLIEAS NSQGTTKLPF KLNIKYAATI
TKTSDLVLVE MGKTAYLECT VDANPITADL IKWQRKPNYI ENSMDDSLES TFSSSTLPNE
FISMDEERFK ITLEENRSFL SVFNITESDS GAYECLASNG IGSPDKATTN LVVKHKPRII
NSPILSKSAS DNGSKGKLIC RAQGAPNITF QWLREGAIIS DKPGNTKYNT EPAEQLNLIT
YQSVLIINEV ANSDYGPYDC VASNELGINR LTVHFNHTSQ PDPPLVLKVV NRTSSSVTLK
WIPGFDGGLP QSFRIRYQKV DATGSTTLPS PNPTSSASLP NTQSTPDASS SISTEPAQYS
DVYPSNTTIY TIKGLTDNTE YSFNVMAYND LGESKYTHDI VKGKTLQETP ISETERISQV
FSGRSGDVPR LIIIAVSILG SSLLLLNVVL VVCFVRKRRK KRLEEEADGS STNKPTTIEM
YAPASGSGGS YTNGPNETSL SGSDEEKHSE GAYSGHTDYD MEMNPGDTLN GNQQNIHPNI
HSYMHGNIHQ SLSTYLIDDT LDHVTSYYQP MFGQENKCIN IPPVPPLRSI NLASFLPMIN
EEPLFINSSP LGHLV
//
