ID T1K7C7_TETUR Unreviewed; 932 AA.
AC T1K7C7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:tetur06g03760.1};
GN Name=107361182 {ECO:0000313|EnsemblMetazoa:tetur06g03760.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur06g03760.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur06g03760.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; CAEY01001802; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015783422.1; XM_015927936.1.
DR AlphaFoldDB; T1K7C7; -.
DR EnsemblMetazoa; tetur06g03760.1; tetur06g03760.1; tetur06g03760.
DR GeneID; 107361182; -.
DR KEGG; tut:107361182; -.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007257_1_1_1; -.
DR OMA; FICNCRE; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR CDD; cd06382; PBP1_iGluR_Kainate; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001508; Iono_Glu_rcpt_met.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PRINTS; PR00177; NMDARECEPTOR.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Signal {ECO:0000256|SAM:SignalP}; Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..932
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004580377"
FT TRANSMEM 559..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 427..797
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 437..503
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 932 AA; 106413 MW; D81C2DC306928DB9 CRC64;
MESTWLIQIL TFLLLTVNLN FINALPEILR IGGLFEVGDD PMEMAFKSAV DRINSDGKLI
PRSRLLAQVE KVEKSDSFSA SKKACGLFEQ GIAAIFGPQS VETSTHIQST CDQLHIPHME
TRLDFRSVAA NHSINLHPHP KVFGEAIRDL IRMKNWKNFA ILYQENEALV RLEEILKDEV
LREKKMVVRQ FETDEYRTIF KEVNKLNIKN LIVDVPRENI HEVLRHAQQV DMLSEYHDYI
FTSLDLQTVD LEDFQYAGTN ISSFCLIDRS STDFKEIIRE WQSSVPVTRT NWLEEDPFIS
RASLLQNFTT EVALMYDSVK LLAKALHDLD RSKTINMNAL SCENEEPWQY GITLTNYMRM
ITVRGLTGDI KFDRNGLRTD VRLKLIELTN EGLKEVGEWT SEKRVQFIGN YSKTMEEILK
ATLKNKTLVV TTFPGRPYTM FVEDYEKKGL TGNDRFEGYC IDLMNEIAKR LQFKYVIRLV
EDRAYGRRNE KGEWNGMIRE LIDGKADIAV ADLTITYERE SAVDFTMPFM NLGIGILFRK
PKKEPPRLFS FMSPLAIEVW IYLLTAFLGV TLFLFVIARF SPYEWINPHP CIKTPEDLEN
NFTMKNTLWF TIGCLMQQGC DVMPRALSTR VLAASWWFFI LILVSSYTAN LAAFLTVERM
VNPIESVEDL AKQTKIHYGC LMSGSTQAFF KNSNFSTYAR MWSFMESTRP SVFVESNDKG
VERVKKGDYA YLMESTSIEY IVERECDLYQ VGGLLDSKGY GIATPPDSPY RGIISDTILA
LQEKGILQAI KEKWWSQKKC GPKDGTQKAA GAASELGLAN VGGVFVVLAI GSVCAVIICI
FEFIWKMKQI PRGERDHIFV ELMRELKHVI CCYGSTRPVR RTGMDDMGSQ IIMQTPGNGI
PGMPIPGYGF PHPIHAHGDF IPAFGMGKED YS
//
