ID T1KHD2_TETUR Unreviewed; 812 AA.
AC T1KHD2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Sec23/Sec24 trunk domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=107364020 {ECO:0000313|EnsemblMetazoa:tetur11g03970.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur11g03970.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur11g03970.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAEY01000075; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015786781.1; XM_015931295.1.
DR AlphaFoldDB; T1KHD2; -.
DR STRING; 32264.T1KHD2; -.
DR EnsemblMetazoa; tetur11g03970.1; tetur11g03970.1; tetur11g03970.
DR GeneID; 107364020; -.
DR KEGG; tut:107364020; -.
DR eggNOG; KOG1985; Eukaryota.
DR HOGENOM; CLU_004589_2_1_1; -.
DR OMA; CILCKHI; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF39; SECRETORY 24AB, ISOFORM A; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 98..134
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 172..402
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 432..515
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 527..625
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 649..701
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 325..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 91576 MW; 765AC371A4E15B79 CRC64;
MVQQMVQQFG SMSVQNNWSS LWGQEGVNLL ADRNIKTKTV DIVPGQDTRD CNRNVMRSTL
QKVPETASLL QKSRLPFGLL IHPFCDYENI PIIQDRTIVR CRNCRTYLNP FVRLLDQRRW
QCNICHRVND LPDDFLVDPV THKLINYPLD QPELSHATVE FVASVEYMVR PPQPAAYLFV
FDCSAHAFHL GYLPVMADTI YSCLNSIPGD TRTMIGFIGF DSRIHFFNLG DKKPQHMIMP
DIKDVFIPSP ESLLVNLHSK RPVIEHFLYK TLKELFNHDG VSQPVAVDSG SAMGSALSAA
YEVISSIGGR ITVIQATLPS LGPDGSVLAN REDPNNRASN SSNTAQLTPL LNPATDFYKK
LALDCSEHHV AVDLFNLSPT FSDLATVGQV AKVSGGSVFY YGATGANMAT NPGRVLARFS
TDLVHYLCRN IGFEAVMRLR CTKGLSIHTF HGNFFVRSTD LISLPNCNPD NGYAMQISID
EDFKDFNSVC FQAAVLYTNP AGERRIRVHT LNLPIVSTLS DVINFADQEA ITAMLCKMAV
DRSMSSNISD AREAMINAIL DLLSTYRNVA PYEASYGLTT SYSTRLLPLY ISALLKHTAF
RVGISTKIDE RVYAMERLKS LPICHITTYI YPDLYPVHTE FNPFAGEYPK PVQLSFANVD
RNGVYLLDTY ECIYLYICKS VNHQWLSDVF GVTQWAKIPD DGDYYSDGGD PKVSKTSRYS
THHNLHNDSS NRLPATPTSV TPLPRLDNPT SMRLNAFIDY LMSSRPLMPH FFLLREDSRL
RYSFLQYMYD DRSESAFSYY EFLQHLQSQL KG
//
