ID T1KLF1_TETUR Unreviewed; 737 AA.
AC T1KLF1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};
GN Name=107365324 {ECO:0000313|EnsemblMetazoa:tetur14g02220.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur14g02220.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur14g02220.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the POU transcription factor family.
CC {ECO:0000256|RuleBase:RU361194}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAEY01000211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015788294.1; XM_015932808.1.
DR AlphaFoldDB; T1KLF1; -.
DR STRING; 32264.T1KLF1; -.
DR EnsemblMetazoa; tetur14g02220.1; tetur14g02220.1; tetur14g02220.
DR GeneID; 107365324; -.
DR KEGG; tut:107365324; -.
DR eggNOG; KOG3802; Eukaryota.
DR HOGENOM; CLU_376583_0_0_1; -.
DR OrthoDB; 2999029at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR013847; POU.
DR InterPro; IPR000327; POU_dom.
DR PANTHER; PTHR11636; POU DOMAIN; 1.
DR PANTHER; PTHR11636:SF5; POU DOMAIN MOTIF 3, ISOFORM F; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF00157; Pou; 1.
DR PRINTS; PR00028; POUDOMAIN.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00352; POU; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00035; POU_1; 1.
DR PROSITE; PS00465; POU_2; 1.
DR PROSITE; PS51179; POU_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Transcription {ECO:0000256|RuleBase:RU361194}.
FT DOMAIN 530..604
FT /note="POU-specific"
FT /evidence="ECO:0000259|PROSITE:PS51179"
FT DOMAIN 623..683
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 625..684
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 202..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 77604 MW; B66CECE5892CEB6E CRC64;
MTTFIQTSPG SYITQQSSNI VDTFSPSPIN STIYTSSSTT STGSSSISSG PTSVSSSLTL
SSSSSSVLPS SSSLTSSSCT ASTASASAAS TGSQLISTQA FGPGTATLLT SQGGSLVLSP
RNVSGLPSYS SSTPSTTIML PLQGNGGTGN GGTGIVNDQL IGNQLLSTIQ PSQQIVSPMV
PLLLANGQLI STGLPSQGAF SLSQATTSTT PSATTSTSNQ QQSQQQQQPQ QYQFGNFIGT
SLTTSLPTNP STQFVTNGSG QIFAISPSLI NNLNQQQSQA TINSLQPHQS SSAFIQVVTP
NGIAIVPANS IISDQPLMST INNNQMDNSS VQQHQQQLLQ QQHQQHHHHQ QHSHHPSMIT
ERERPSKRAS QSKGSFYSRN DNNGEGGGNS RMMKKSASNQ ANDGQMNQAI QVSISSGASS
SSASTNTKNS GRMGPSNHGF SNQSSLASLN CYNRNSDLKP LAMNNGNNSG NANCPSQQTM
FLNNQSNNPV SNSAESQTPS PPLSTASSME PESNQATVAQ TINNSDEAVV DGVNLEEVKE
FARQFKLRRL SLGLTQTQVG QALSATAGPS YSQSAICRFE KLDITPKSAS KIKPVLEKWM
HDLEIRCRAG STDPAAFTGN PNSKKRKRRT SFTPSALEVL NAFFEKNTHP SSSEMTELAD
KLKYDREVVR VWFCNKRQVL RNNVKKSEPP LSLLTLTSRA AKAKAAAAAE AASAAPSSSS
SLPSTSTLSS NNNVLIA
//
