ID   T1L399_TETUR            Unreviewed;       616 AA.
AC   T1L399;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Tetranychus urticae (Two-spotted spider mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC   Tetranychoidea; Tetranychidae; Tetranychus.
OX   NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur35g00740.1, ECO:0000313|Proteomes:UP000015104};
RN   [1] {ECO:0000313|Proteomes:UP000015104}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA   Rombauts S.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:tetur35g00740.1}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   EMBL; CAEY01001015; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1L399; -.
DR   STRING; 32264.T1L399; -.
DR   EnsemblMetazoa; tetur35g00740.1; tetur35g00740.1; tetur35g00740.
DR   eggNOG; KOG0922; Eukaryota.
DR   HOGENOM; CLU_001832_5_11_1; -.
DR   OMA; KVKVWRH; -.
DR   Proteomes; UP000015104; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015104}.
FT   DOMAIN          36..214
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          236..410
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   616 AA;  69677 MW;  994FC3B570904E61 CRC64;
     MNSNHVGGKS HANHASSESL SSTSLLTIHQ YRSKLMDIID TEPIFVLIGA TGSGKTTQLP
     QWCLQSKHSV GESEGSLTSK CRVVGITQPR RVAAVSIATR VANEMKTNLG QLVGYSVRFD
     EVLSPATRIK FMTDGMLLRE SLYDPLLRKY SFIILDEAHE RSIQTDILFA IVKKAFHARK
     KNGLSSLRVV IMSATMNVDK FSNYFDQCPV FKIAGRHHPI EILHAEQDLT DTIHASLVTV
     FQIHRTQPTG DILVFCTGQE EIENMVSVTR ETCFQLPQEQ RNLVPLPLYA ALPFNAQFKI
     FKSFSGKRKV IFATNIAETS ITISGIKYVV DCGKFKCRRY KPSSGMDTLK IETISQAQAW
     QRAGRAGRES SGICYRLYSR ETYENMPKEM VPEMLRCNLA SVLLHLAAIG IKDFTKFDFM
     DKPSIENVNK STELLISLGA ITKDENNWYQ ITHLGRQMVN FPLDPRLAKI LIASAELGCS
     EEILSVISLL SVENVFHIPP HKKEEANEVH KKFRSTEGDH VMLLKLYRAY KAAKGNKEWC
     KENYIDFRNM RMVANIRQQM AALYERTNFT KNSCGANTEL VRKCITVGLY HNLAVIGKEG
     EYRTIFNYCE IHLFNS
//