ID T1NXH0_OCIBA Unreviewed; 361 AA.
AC T1NXH0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Caffeic acid O-methyltransferase {ECO:0000313|EMBL:ADO16248.1};
OS Ocimum basilicum (Sweet basil).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ociminae;
OC Ocimum.
OX NCBI_TaxID=39350 {ECO:0000313|EMBL:ADO16248.1};
RN [1] {ECO:0000313|EMBL:ADO16248.1}
RP NUCLEOTIDE SEQUENCE.
RA Rastogi S., Shasany A.K.;
RT "Phenylpropanoid biosynthetic pathway in Ocimum.";
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Cation-independent O-methyltransferase family. COMT
CC subfamily. {ECO:0000256|ARBA:ARBA00034481}.
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DR EMBL; HM990154; ADO16248.1; -; mRNA.
DR AlphaFoldDB; T1NXH0; -.
DR SMR; T1NXH0; -.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF199; FLAVONE 3'-O-METHYLTRANSFERASE 1; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ADO16248.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:ADO16248.1}.
FT DOMAIN 32..83
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 138..343
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 267
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 361 AA; 39613 MW; 4B8CA0825E6B65D0 CRC64;
MSSTANNPQI NSDEEENFLF AMQLASASVL PMVLKSAIEL DLLELIKKAG AGAFVSPAEL
AAQLLTTNAE AHVMLDRILR LLTSYAILEC RLKTLPDGGV QRLYGLAPVC KFLTKNEDGV
SMAPLALMNQ DKVLMESWYH LKDAVLDGGI PFNKAYGMTA FEYHGTDPRF NKVFNQGMSN
HSTITMKKIL ETYTGFDGLK TVVDVGGGTG ATLNMIISKY PSIKGINFDL PHVVEDAPSY
PGVEHVGGDM FVSVPKGDAI FMKWICHDWS DAHCVKFLKK CYEALPENGK VILAECVLPE
APDTGLATKN VVHIDVIMLA HNPGGKERTE KEFQVLAKAS GFKQFNKVCC AYNSWIMELL
K
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